Active Ingredient History

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Vildagliptin, sold under the brand name GALVUS In India as ZAVAMET and others, is an oral anti-hyperglycemic agent of the dipeptidyl peptidase-4 (DPP-4) inhibitor class of drugs. Vildagliptin inhibits the inactivation of GLP-1 and GIP by DPP-4, allowing GLP-1 and GIP to potentiate the secretion of insulin in the beta cells and suppress glucagon release by the alpha cells of the islets of Langerhans in the pancreas.   Wikipedia

  • SMILES: OC12CC3CC(C1)CC(C3)(C2)NCC(=O)N4CCC[C@H]4C#N
  • InChIKey: SYOKIDBDQMKNDQ-XWTIBIIYSA-N
  • Mol. Mass: 303.41
  • ALogP: 1.17
  • ChEMBL Molecule:
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1-(((3-hydroxy-1-adamantyl)amino)acetyl)-2-cyanopyrrolidine | (2s)-(((3-hydroxyadamantan-1-yl)amino)acetyl)pyrrolidine-2-carbonitrile | equa | galvus | haaa-2-cyanopyrrolidine | jalra | laf237 | laf 237 | laf-237 | nvp-laf237 | nvp-laf-237 | vidagliptin | vildagliptin | vildagliptin hcl | vildagliptin hydrochloride | vildagliptin / metformin hydrochloride | xiliarx

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