vedolizumab (entyvio) Report issue

Biologics mAb Approved FDA First in Class Fast Track FDA
AACT ChEMBL DrugBank Drug Central Drugs@FDA KEGG MeSH repoDB

Active Ingredient History

NOW
  • Now
Vedolizumab, sold under the brand name Entyvio, is a monoclonal antibody medication developed by Millennium Pharmaceuticals, Inc. for the treatment of ulcerative colitis and Crohn's disease. It binds to integrin α4β7. Blocking the α4β7 integrin results in gut-selective anti-inflammatory activity.   Wikipedia

Chemistry

More Chemistry

Pharmacology

  • Mechanisms of Action:
  • Multi-specific: No
  • Black Box: No
  • Availability: Prescription Only
  • Delivery Methods: Parenteral
  • Pro Drug: No

Drug Pricing (per unit)

Australia

$2407.4538

United States

$4573.8400 - $6255.2200
More Pricing Detail

Note: This drug pricing data is preliminary, incomplete, and may contain errors.

Alternative names

entyvio | ldp02 | ldp-02 | mln0002 | mln-0002 | mln02 | mln-02 | vedolizumab

Organizations (62)

Research & Development (62)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Marketing (1)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Indications (21)

Approved Indications (2)


 

Colitis, Ulcerative

Crohn Disease

Experimental Indications - Clinical Trial Phases 1-4 (21)


 

Carcinoma, Non-Small-Cell Lung (Phase 1/Phase 2)

Celiac Disease (Phase 2)

Cholangitis, Sclerosing (Phase 3)

Colitis (Phase 1/Phase 2)

Colitis, Ulcerative ()

Crohn Disease ()

Diet Therapy (Early Phase 1)

Graft vs Host Disease (Phase 2)

Healthy Volunteers (Phase 1)

Hematopoietic Stem Cells (Phase 3)

Hematopoietic Stem Cell Transplantation (Phase 2)

HIV (Phase 1)

HIV Infections (Phase 2)

Immune System Diseases (Phase 2)

Inflammatory Bowel Diseases (Phase 4)

Lung Neoplasms (Early Phase 1)

Melanoma (Phase 1/Phase 2)

Neoplasm Metastasis (Phase 1/Phase 2)

Neoplasms (Phase 1/Phase 2)

Pouchitis (Phase 4)

Psoriasis (Phase 4)

Overview

  • Highest Phase: Phase 4
  • # of Trials: 82
  • # of Trial Organizations: 62

Trials by Phase

Trial Phase Start Date Organizations Indications

Feedback

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