Active Ingredient History
Lipopolysaccharides (LPS) are large molecules consisting of a lipid and a polysaccharide that are bacterial toxins. They are composed of an O-antigen, an outer core, and an inner core all joined by covalent bonds, and are found in the outer membrane of Gram-negative bacteria. Today, the term endotoxin is often used synonymously with LPS, although there are a few endotoxins that are not related to LPS, such as the so-called delta endotoxin proteins produced by Bacillus thuringiensis. Wikipedia
| Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
|---|
| Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
|---|
Acute Lung Injury (Phase 2)
Alcoholism (Phase 2)
Anhedonia (Phase 1)
Asthma (Phase 1)
Cigarette Smoking (Phase 1)
Craving (Phase 2)
Depression (Phase 2)
Endotoxemia (Phase 3)
Fever (Phase 3)
Healthy Volunteers (Phase 4)
Hypersensitivity (Phase 1)
Immune System (Phase 1)
Immunity, Innate (Phase 3)
Infections (Phase 1)
Inflammation (Phase 3)
Leukemia, Lymphocytic, Chronic, B-Cell (Phase 1/Phase 2)
Leukemia, Myeloid, Acute (Phase 1/Phase 2)
Leukemia, Myeloid, Chronic-Phase (Phase 1/Phase 2)
Lung Diseases (Phase 1)
Lymphoma, Non-Hodgkin (Phase 1/Phase 2)
Myelodysplastic Syndromes (Phase 1/Phase 2)
Pneumonia (Phase 1)
Respiratory Distress Syndrome (Phase 1)
Rhinitis, Allergic (Phase 1)
Rhinitis, Allergic, Perennial (Phase 1)
Rhinitis, Allergic, Seasonal (Phase 1)
Sepsis (Phase 3)
Shock, Septic (Phase 1)
| Trial | Phase | Start Date | Organizations | Indications |
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