Active Ingredient History

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Trospium is an antispasmodic, antimuscarinic agent indicated for the treatment of overactive bladder with symptoms of urge urinary incontinence, urgency, and urinary frequency. Receptor assays showed that trospium has negligible affinity for nicotinic receptors as compared to muscarinic receptors at concentrations obtained from therapeutic doses. Trospium antagonizes the effect of acetylcholine on muscarinic receptors in cholinergically innervated organs. Its parasympatholytic action reduces the tonus of smooth muscle in the bladder. Trospium is marketed under the brand name Sancturain the US, Tropez OD in India,Trosec in Canada, Regurin and Flotros in the United Kingdom and Spasmex in Germany, Russia, Turkey, Argentina, Chile and Israel.   NCATS

  • SMILES: OC(C(=O)O[C@H]1C[C@H]2CC[C@@H](C1)[N+]23CCCC3)(c4ccccc4)c5ccccc5
  • Mol. Mass: 392.52
  • ALogP: 3.77
  • ChEMBL Molecules:
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Drug Pricing (per unit)

United States

$0.2643 - $3.6107
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Note: This drug pricing data is preliminary, incomplete, and may contain errors.

azoniaspiro(3 alpha-benziloyloxynortropane-8,1'- pyrrolidine) chloride | azoniaspiro compound xvii | ceris | flotros | ip631 | regurin | regurin xl | relaspium | sanctura | spasmex | spasmolyt | spasmo-lyt | spasmo-rhoival tc | spasmo-urgenin | spasmo-urgenin tc | trosec | trospi | trospium | trospium chloride | uraplex | uraton


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