Active Ingredient History

  • Now
Dapsone was synthesized in 1908 by Fromm and Wittmann. The drug was approved by FDA for the treatment of such conditions as acne vulgaris, leprosy and dermatitis herpetiformis, also the drug is used off-label for many skin diseases. Although the exact mechanism of dapsone action is unknown, it is speculated that it acts as both anti-inflammatory and antimicrobial agent. It was demonstrated that dapsone suppresses ROS generation, inhibits neutrophil myeloperoxidase and eosinophil peroxidase and also inhibits bacterial dihydropteroate synthase.   NCATS

  • SMILES: NC1=CC=C(C=C1)S(=O)(=O)C2=CC=C(N)C=C2
  • Mol. Mass: 248.301
  • ALogP: 1.68
  • ChEMBL Molecule:
More Chemistry
  • Mechanism of Action:
  • Multi-specific: Missing data
  • Black Box: No
  • Availability: Prescription Only
  • Delivery Methods: Oral, Topical
  • Pro Drug: No

Drug Pricing (per unit)

United States

$0.4797 - $11.2843


$1.8175 - $2.2303
More Pricing Detail

Note: This drug pricing data is preliminary, incomplete, and may contain errors.

1,1'-sulfonylbis(4-aminobenzene) | 1,1'-sulfonylbis[4-aminobenzene] | 4-(4-amino-benzenesulfonyl)-phenylamine | 4-(4-aminophenylsulfonyl)aniline | 4-(4-aminophenylsulfonyl)benzenamine | 4,4'-dapsone | 4,4'-diaminodiphenylsulfone | 4,4'-diaminodiphenyl sulfone | 4,4'-diaminodiphenyl sulphone | 4,4'-sulfonylbisaniline | 4,4'-sulfonylbisbenzenamine | 4,4'-sulfonylbisbenzeneamine | 4,4'-sulfonyldianilin | 4,4'-sulfonyldianiline | 4-aminophenyl sulfone | aczone | bis(4-aminophenyl)sulfone | bis(p-aminophenyl) sulfone | dadps | dapson | dapsona | dapsone | dapsone mixture with pyrimethamine | dapsonum | dds | diaminodiphenylsulfone | diaphenylsulfon | diaphenylsulfone | p-aminophenyl sulfone | p,p'-diaminodiphenyl sulfone | p,p-sulphonylbisbenzamine | p,p-sulphonylbisbenzenamine | sulphadione


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