API | anifrolumab

anifrolumab (Saphnelo) Report issue

Biologics mAb Approved ^FDA Fast Track ^FDA

AACT ChEMBL DrugBank

Active Ingredient History

NOW

Anifrolumab, sold under the brand name Saphnelo, is a monoclonal antibody used for the treatment of systemic lupus erythematosus (SLE). It binds to the type I interferon receptor, blocking the activity of type I interferons such as interferon-α and interferon-β. ^Wikipedia

Chemistry

SMILES: Missing data
InChIKey: Missing data
Mol. Mass: Missing data
ALogP: Missing data
ChEMBL Molecule:
anifrolumab

More Chemistry

Pharmacology

Mechanisms of Action:
- Interferon alpha/beta receptor 1 (Homo sapiens) ^UniProt
Multi-specific: No
Black Box: No
Availability: Missing data
Delivery Methods: Missing data
Pro Drug: No

anifrolumab | medi-546

Organizations (13)

Research & Development (13)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Marketing (1)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Indications (7)

Approved Indications (1)

Lupus Erythematosus, Systemic (approved 2021)

Experimental Indications - Clinical Trial Phases 1-4 (7)

Arthritis, Rheumatoid (Phase 2)

Healthy Volunteers (Phase 1)

Lupus Erythematosus, Systemic (Phase 3)

Lupus Nephritis (Phase 3)

Pharmacokinetics (Phase 1)

Safety (Phase 1)

Scleroderma, Systemic (Phase 1)

Overview

Highest Phase: Phase 3
# of Trials: 20
# of Trial Organizations: 13

Trials by Phase

Trial	Phase	Start Date	Organizations	Indications

Feedback

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