Active Ingredient History

  • Now
Tivantinib is an experimental small molecule anti-cancer drug. It is a bisindolylmaleimide that binds to the dephosphorylated MET kinase in vitro. Tivantinib is being tested clinically as a highly selective MET inhibitor. However, the mechanism of action of tivantinib is still unclear.   Wikipedia

  • SMILES: O=C1NC(=O)[C@@H]([C@H]1C2=CNC3=C2C=CC=C3)C4=CN5CCCC6=CC=CC4=C56
  • Mol. Mass: 369.4159
  • ALogP: 3.59
  • ChEMBL Molecule:
More Chemistry
arq197 | arq 197 | arq-197 | tiv | tivantinib | tivantinib (arq 197) | (-)-trans-3-(5,6-dihydro-4h-pyrrolo(3,2,1-ij)quinolin-1-yl)-4-(1h-indol-3-yl)pyrrolidin-2,5-dione


Data collection and curation is an ongoing process for CDEK - if you notice any information here to be missing or incorrect, please let us know! When possible, please include a source URL (we verify all data prior to inclusion).

Report issue