Active Ingredient History

  • Now
Tezosentan is a non-selective ETA and ETB receptor antagonist. It acts as a vasodilator and was designed by Actelion as a therapy for patients with acute heart failure. However, studies showed that tezosentan did not improve dyspnea or reduce the risk of fatal or nonfatal cardiovascular events.   Wikipedia

  • SMILES: COc1ccccc1Oc2c(NS(=O)(=O)c3ccc(cn3)C(C)C)nc(nc2OCCO)c4ccnc(c4)c5nn[nH]n5
  • Mol. Mass: 605.64
  • ALogP: 3.21
  • ChEMBL Molecule:
More Chemistry
5-isopropyl-pyridine-2-sulfonic acid 6-(2-hydroxy-ethoxy)-5-(2-methoxy-phenoxy)-2-(2-1h-tetrazol-5-yl--pyridin-4-yl)--pyrimidin-4-ylamide | act-050089 | ro 610612 | ro 61-0612 | ro-610612 | ro-61-0612 | tezosentan


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