Active Ingredient History

  • Now
Temazepam is a benzodiazepine used as a hypnotic agent in the management of insomnia. Temazepam produces CNS depression at limbic, thalamic, and hypothalamic levels of the CNS. Temazepam increases the affinity of the neurotransmitter gamma-aminobutyric acid (GABA) for GABA receptors by binding to benzodiazepine receptors. Results are sedation, hypnosis, skeletal muscle relaxation, anticonvulsant activity, and anxiolytic action. Benzodiazepines bind nonspecifically to benzodiazepine receptors, which affects muscle relaxation, anticonvulsant activity, motor coordination, and memory. As benzodiazepine receptors are thought to be coupled to gamma-aminobutyric acid-A (GABAA) receptors, this enhances the effects of GABA by increasing GABA affinity for the GABA receptor. Binding of the inhibitory neurotransmitter GABA to the site opens the chloride channel, resulting in a hyperpolarized cell membrane that prevents further excitation of the cell. Temazepam is used for the short-term treatment of insomnia (generally 7-10 days).   NCATS

  • SMILES: CN1C2=CC=C(Cl)C=C2C(=NC(O)C1=O)C3=CC=CC=C3
  • Mol. Mass: 300.74
  • ALogP: 2.47
  • ChEMBL Molecule:
More Chemistry

Drug Pricing (per unit)


$0.0375 - $0.1414

United States

$0.0600 - $24.9700
More Pricing Detail

Note: This drug pricing data is preliminary, incomplete, and may contain errors.

kentepam | levanxene | levanxol | normison | restoril | (rs)-temazepam | temaz | temazepam | wy-3917


Data collection and curation is an ongoing process for CDEK - if you notice any information here to be missing or incorrect, please let us know! When possible, please include a source URL (we verify all data prior to inclusion).

Report issue