fosamprenavir (lexiva) Report issue

Small molecule Approved FDA Fast Track FDA
AACT ChEMBL DrugBank Drug Central Drugs@FDA KEGG MeSH PubChem repoDB

Active Ingredient History

NOW
  • Now
Fosamprenavir, sold under the brand names Lexiva and Telzir, is a medication used to treat HIV/AIDS. It is a prodrug of the protease inhibitor and antiretroviral drug amprenavir. It is marketed by ViiV Healthcare as the calcium salt.   Wikipedia

Chemistry

  • SMILES: CC(C)CN(C[C@@H](OP(=O)(O)O)[C@H](Cc1ccccc1)NC(=O)O[C@H]2CCOC2)S(=O)(=O)c3ccc(N)cc3
  • InChIKey: MLBVMOWEQCZNCC-OEMFJLHTSA-N
  • Mol. Mass: 585.62
  • ALogP: 2.52
  • ChEMBL Molecules:
    fosamprenavir  
    fosamprenavir calcium  
More Chemistry

Pharmacology

  • Mechanism of Action:
  • Multi-specific: Missing data
  • Black Box: No
  • Availability: Prescription Only
  • Delivery Methods: Oral
  • Pro Drug: Yes

Drug Pricing (per unit)

United States

$0.5772 - $19.0185

Australia

$3.9795
More Pricing Detail

Note: This drug pricing data is preliminary, incomplete, and may contain errors.

Alternative names

(3-(((4-aminophenyl)sulfonyl)(2-methylpropyl)amino)-1-(phenylmethyl)-2-(phosphonooxy)propyl)carbamic acid c-(tetrahydro-3-furanyl) ester | amprenavir phosphate | fosamprenavir | fos-amprenavir | fosamprenavir calcium | gw433908 | gw 433908 | gw-433908 | gw433908g | gw 433908g | gw-433908g | gw 908 | gw-908 | gw908 cpd | lexiva | telzir | vx 175 | vx-175 | vx175 cpd

Organizations (52)

Research & Development (49)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Marketing (5)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Indications (14)

Approved Indications (1)


 

HIV Infections

Experimental Indications - Clinical Trial Phases 1-4 (14)


 

Acquired Immunodeficiency Syndrome (Phase 3)

Analgesics, Opioid (Phase 1)

Drugs, Investigational (Phase 1)

Healthy Volunteers (Phase 2)

Hepatitis C (Phase 4)

HIV (Phase 4)

HIV-1 (Phase 4)

HIV Infections ()

Hypertriglyceridemia (Phase 4)

Laryngopharyngeal Reflux (Phase 3)

Mycoses (Phase 1)

Premature Ejaculation (Phase 1)

Proteinuria (Phase 4)

Sexually Transmitted Diseases, Viral (Phase 1)

Overview

  • Highest Phase: Phase 4
  • # of Trials: 47
  • # of Trial Organizations: 49

Trials by Phase

Trial Phase Start Date Organizations Indications

Feedback

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