Active Ingredient History

  • Now
Telapristone (INN), as telapristone acetate, is a synthetic, steroidal selective progesterone receptor modulator (SPRM) related to mifepristone which is under development by Repros Therapeutics for the treatment of breast cancer, endometriosis, and uterine fibroids. It was originally developed by the National Institutes of Health (NIH), and, as of 2017, is in phase II clinical trials for the aforementioned indications. In addition to its activity as an SPRM, the drug also has some antiglucocorticoid activity.   Wikipedia

  • SMILES: COCC(=O)[C@]1(CC[C@H]2[C@@H]3CCC4=CC(=O)CCC4=C3[C@H](C[C@]12C)c5ccc(cc5)N(C)C)OC(=O)C
  • Mol. Mass: 505.66
  • ALogP: 5.17
  • ChEMBL Molecule:
More Chemistry
cdb4124 | cdb 4124 | cdb-4124 | proellex | progenta | ru-44675 | telapristone acetate


Data collection and curation is an ongoing process for CDEK - if you notice any information here to be missing or incorrect, please let us know! When possible, please include a source URL (we verify all data prior to inclusion).

Report issue