Active Ingredient History
Arbaclofen placarbil is a prodrug of R-baclofen. Arbaclofen placarbil possesses more favorable pharmacokinetic profile than baclofen, with less fluctuations in plasma drug levels. It was being developed as a potential treatment for patients with GERD and spasticity due to multiple sclerosis; however, in May 2013 XenoPort announced the termination of development because of unsuccessful results in phase III clinical trials. Wikipedia
| Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
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| Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
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Alcoholism (Phase 2)
Autism Spectrum Disorder (Phase 3)
Fragile X Syndrome (Phase 3)
Multiple Sclerosis (Phase 3)
Muscle Spasticity (Phase 3)
Spermatozoa (Phase 3)
Substance Withdrawal Syndrome (Phase 2)
| Trial | Phase | Start Date | Organizations | Indications |
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