API | ganetespib

ganetespib Report issue

Small molecule Experimental

AACT ChEMBL DrugBank MeSH PubChem

Active Ingredient History

NOW

Now

Chemistry

SMILES: CC(C)c1cc(C2=NNC(=O)N2c3ccc4c(ccn4C)c3)c(O)cc1O
InChIKey: RVAQIUULWULRNW-UHFFFAOYSA-N
Mol. Mass: 364.41
ALogP: 3.25 Partition coefficient
ChEMBL Molecule:
ganetespib

More Chemistry

Pharmacology

Mechanism of Action:
- Heat shock protein HSP 90-alpha (Homo sapiens) ^UniProt
- Heat shock protein HSP 90-beta (Homo sapiens) ^UniProt
Multi-specific: Missing data
Black Box: No
Availability: Missing data
Delivery Methods: Missing data
Pro Drug: No

ganetespib | sta9090 | sta 9090 | sta-9090

Organizations (26)

Research & Development (26)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Marketing (0)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Indications (34)

Approved Indications (0)

Experimental Indications - Clinical Trial Phases 1-4 (34)

Breast Neoplasms (Phase 2)

Breast Neoplasms, Male (Phase 1)

Carcinoma, Hepatocellular (Phase 1)

Carcinoma, Non-Small-Cell Lung (Phase 3)

Carcinoma, Ovarian Epithelial (Phase 1/Phase 2)

Carcinoma, Squamous Cell (Phase 1)

Colonic Neoplasms (Phase 2)

Esophageal Neoplasms (Phase 2)

Fallopian Tube Neoplasms (Phase 2)

Gastrointestinal Stromal Tumors (Phase 2)

Hamartoma (Phase 2)

Hemangiosarcoma (Phase 2)

Leukemia, Lymphoid (Phase 1)

Leukemia, Myelogenous, Chronic, BCR-ABL Positive (Phase 1)

Leukemia, Myeloid, Acute (Phase 3)

Leukemia, Myeloid, Chronic-Phase (Phase 1)

Lung Neoplasms (Phase 1)

Melanoma (Phase 2)

Mesothelioma (Phase 2)

Multiple Myeloma (Phase 1)

Myelodysplastic Syndromes (Phase 3)

Myeloproliferative Disorders (Phase 1)

Neoplasm Metastasis (Phase 1)

Neoplasms (Phase 2)

Nerve Sheath Neoplasms (Phase 2)

Ovarian Neoplasms (Phase 2)

Pancreatic Neoplasms (Phase 2)

Precursor Cell Lymphoblastic Leukemia-Lymphoma (Phase 1)

Prostatic Neoplasms (Phase 2)

Rectal Neoplasms (Phase 2)

Sarcoma (Phase 1/Phase 2)

Small Cell Lung Carcinoma (Phase 2)

Squamous Cell Carcinoma of Head and Neck (Phase 1)

Triple Negative Breast Neoplasms (Phase 2)

Overview

Highest Phase: Phase 3
# of Trials: 39
# of Trial Organizations: 26

Trials by Phase

Trial	Phase	Start Date	Organizations	Indications

Feedback

Data collection and curation is an ongoing process for CDEK - if you notice any information here to be missing or incorrect, please let us know! When possible, please include a source URL (we verify all data prior to inclusion).

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