Active Ingredient History
Aspirin is a nonsteroidal anti-inflammatory drug. Aspirin is unique in this class of drugs because it irreversibly inhibits both COX-1 and COX-2 activity by acetylating a serine residue (Ser529 and Ser516, respectively) positioned in the arachidonic acid-binding channel, thus inhibiting the synthesis of prostaglandins and reducing the inflammatory response. The drug is used either alone or in combination with other compounds for the treatment of pain, headache, as well as for reducing the risk of stroke and heart attacks in patients with brain ischemia and cardiovascular diseases. NCATS
Drug Pricing (per unit)
Note: This drug pricing data is preliminary, incomplete, and may contain errors.
Combination drugs
| Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
|---|
| Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
|---|
Abortion, Habitual (Phase 4)
Abortion, Spontaneous (Phase 4)
Abruptio Placentae (Phase 3)
Accidents (Phase 4)
Acute Chest Syndrome (Phase 3)
Acute Coronary Syndrome (Phase 4)
Acute Lung Injury (Phase 2)
Adenoma (Phase 2/Phase 3)
Adenomatous Polyps (Phase 3)
Adenomyosis (Early Phase 1)
Aggressive Periodontitis (Phase 2/Phase 3)
Aging (Phase 4)
Air Travel (Phase 2/Phase 3)
Albuminuria (Phase 4)
Allergy and Immunology (Phase 2/Phase 3)
alpha 1-Antitrypsin Deficiency (Phase 2)
Analgesics (Phase 4)
Analgesics, Opioid (Phase 4)
Anemia, Sickle Cell (Phase 1/Phase 2)
Anesthesia (Phase 4)
Aneurysm (Phase 4)
Angina Pectoris (Phase 4)
Angina, Stable (Phase 4)
Angina, Unstable (Phase 4)
Angiogenesis Modulating Agents (Early Phase 1)
Angioplasty, Balloon, Coronary (Phase 4)
Ankle Fractures (Early Phase 1)
Anticoagulants (Phase 4)
Anti-Inflammatory Agents (Phase 4)
Antioxidants (Phase 3)
Antithrombins (Phase 4)
Aorta (Phase 1)
Aortic Stenosis, Subvalvular (Phase 4)
Aortic Valve Disease (Phase 4)
Aortic Valve Insufficiency (Phase 4)
Aortic Valve Stenosis (Phase 4)
Appendix (Phase 4)
Arterial Occlusive Diseases (Phase 4)
Arteriosclerosis (Phase 4)
Arthritis (Phase 4)
Arthritis, Rheumatoid (Phase 4)
Arthroplasty (Phase 4)
Aspirin (Phase 4)
Asthma (Phase 3)
Asthma, Aspirin-Induced (Phase 4)
Atherosclerosis (Phase 4)
Atrial Appendage (Phase 4)
Atrial Fibrillation (Phase 4)
Atrial Function, Left (Phase 3)
Barrett Esophagus (Phase 4)
Bipolar Disorder (Phase 2)
Bleeding Time (Phase 2)
Blindness (Phase 3)
Blood Platelet Disorders (Phase 4)
Blood Platelets (Phase 4)
Blood Pressure (Phase 4)
Body Fluids (Phase 4)
Body Weight (Phase 4)
Brain Death (Phase 3)
Brain Infarction (Phase 3)
Brain Injuries, Traumatic (Phase 4)
Brain Ischemia (Phase 4)
Breast Neoplasms (Phase 3)
CADASIL (Phase 2)
Carcinoma, Hepatocellular (Phase 3)
Carcinoma, Non-Small-Cell Lung (Phase 3)
Carcinoma, Squamous Cell (Phase 3)
Cardiomyopathy, Hypertrophic (Phase 3)
Cardiovascular Diseases (Phase 4)
Carotid Artery Diseases (Phase 4)
Carotid Stenosis (Phase 4)
Cataract (Phase 3)
Cerebral Hemorrhage (Phase 3)
Cerebral Infarction (Phase 4)
Cerebral Small Vessel Diseases (Phase 4)
Cerebrovascular Disorders (Phase 3)
Cervix Uteri (Phase 4)
Chagas Disease (Phase 4)
Chemoradiotherapy (Phase 2)
Chronic Limb-Threatening Ischemia (Phase 4)
Clopidogrel (Phase 1)
Cognition Disorders (Phase 1/Phase 2)
Cognitive Dysfunction (Phase 2)
Cold Temperature (Phase 3)
Colitis, Ulcerative (Phase 3)
Colonic Neoplasms (Phase 3)
Colonic Polyps (Phase 3)
Colorectal Neoplasms (Phase 3)
Common Cold (Phase 4)
Constriction, Pathologic (Phase 3)
Coronary Aneurysm (Phase 2)
Coronary Angiography (Early Phase 1)
Coronary Artery Bypass (Phase 4)
Coronary Artery Bypass, Off-Pump (Phase 3)
Coronary Artery Disease (Phase 4)
Coronary Disease (Phase 4)
Coronary Restenosis (Phase 4)
Coronary Stenosis (Phase 4)
Coronary Thrombosis (Phase 4)
Coronavirus Infections (Phase 2)
COVID-19 (Phase 3)
Craniocerebral Trauma (Phase 4)
Critical Illness (Phase 3)
Crohn Disease (Phase 3)
Dementia (Phase 4)
Dementia, Vascular (Phase 4)
Dental Caries (Phase 4)
Depression (Phase 4)
Depressive Disorder (Phase 2)
Depressive Disorder, Major (Phase 2)
Depressive Disorder, Treatment-Resistant (Phase 2)
Dermatology (Phase 2)
Diabetes Mellitus (Phase 4)
Diabetes Mellitus, Type 1 (Phase 4)
Diabetes Mellitus, Type 2 (Phase 4)
Diabetic Nephropathies (Phase 4)
Diabetic Retinopathy (Phase 3)
Diet Therapy (Phase 2)
Disability Evaluation (Phase 4)
Disseminated Intravascular Coagulation (Phase 2)
Drug-Eluting Stents (Phase 4)
Drug Interactions (Phase 1)
Drugs, Generic (Phase 1)
Drugs, Investigational (Phase 4)
Dual Anti-Platelet Therapy (Phase 4)
Dyslipidemias (Phase 4)
Embolic Stroke (Phase 4)
Embolism (Phase 4)
Embolism and Thrombosis (Phase 2)
Embolism, Paradoxical (Phase 4)
Emphysema (Phase 2)
Endometrial Neoplasms (Phase 2)
Endothelial Cells (Phase 4)
Endothelium (Phase 1/Phase 2)
Endovascular Procedures (Phase 4)
Enoxaparin (Phase 4)
Epidermal Growth Factor (Phase 2)
Epilepsy (Phase 2)
Epithelial-Mesenchymal Transition (Phase 2)
Esophageal Neoplasms (Phase 3)
Essential Hypertension (Phase 4)
Exercise (Phase 2)
Fallopian Tube Diseases (Early Phase 1)
Fallopian Tube Neoplasms (Early Phase 1)
Fatigue (Phase 3)
Fatty Acids (Phase 2)
Feeding and Eating Disorders (Early Phase 1)
Fertilization in Vitro (Phase 4)
Fetal Growth Retardation (Phase 4)
Fever (Phase 4)
Fibrinolysis (Phase 3)
Fibrosis (Phase 4)
Flushing (Phase 4)
Fontan Procedure (Phase 4)
Foramen Ovale, Patent (Phase 4)
Fractures, Bone (Phase 3)
Gastroesophageal Reflux (Phase 4)
Gastrointestinal Hemorrhage (Phase 4)
General Surgery (Phase 3)
Giant Cell Arteritis (Phase 2)
Gingivitis (Phase 2)
Glioblastoma (Phase 2)
Gonadotropin-Releasing Hormone (Phase 4)
Hamartoma (Early Phase 1)
Headache (Phase 4)
Head and Neck Neoplasms (Phase 2)
Healthy Volunteers (Phase 4)
Heart (Phase 4)
Heart Defects, Congenital (Phase 4)
Heart Disease Risk Factors (Phase 4)
Heart Diseases (Phase 4)
Heart Failure (Phase 4)
Heart Septal Defects, Atrial (Phase 4)
Heart Transplantation (Phase 3)
Heart Valve Diseases (Phase 4)
Hematology (Phase 1)
Hematoma (Phase 4)
Hematoma, Subdural, Chronic (Phase 4)
Hematuria (Phase 4)
Hemodilution (Phase 3)
Hemorrhage (Phase 4)
Hemorrhagic Disorders (Phase 4)
Herpes Simplex (Phase 1)
HIV (Phase 2)
HIV Infections (Phase 2)
Hypercholesterolemia (Phase 4)
Hyperlipidemias (Phase 4)
Hypertension (Phase 4)
Hypertension, Portal (Phase 4)
Hypertension, Pregnancy-Induced (Phase 3)
Hypertension, Pulmonary (Phase 2)
Hypertriglyceridemia (Phase 1)
Hypertrophy, Left Ventricular (Phase 4)
Infant, Premature, Diseases (Phase 2)
Infant, Small for Gestational Age (Phase 2)
Infant, Very Low Birth Weight (Phase 2)
Infarction, Middle Cerebral Artery (Phase 3)
Infertility (Phase 3)
Infertility, Female (Early Phase 1)
Inflammation (Phase 2/Phase 3)
Insulin Resistance (Phase 4)
Intermittent Claudication (Phase 4)
Intestinal Neoplasms (Phase 4)
Intracranial Aneurysm (Phase 4)
Intracranial Arteriosclerosis (Phase 3)
Intracranial Embolism (Phase 3)
Intracranial Hemorrhages (Phase 4)
Ischemia (Phase 4)
Ischemic Attack, Transient (Phase 4)
Ischemic Stroke (Phase 4)
Joint Diseases (Phase 3)
Ketorolac (Phase 3)
Kidney Failure, Chronic (Phase 4)
Kidney Transplantation (Phase 4)
Leg Ulcer (Phase 3)
Leukemia, Myeloid, Chronic-Phase (Phase 2)
Livedoid Vasculopathy (Phase 3)
Liver Neoplasms (Phase 2)
Low Back Pain (Phase 3)
Lung Neoplasms (Phase 2)
Lupus Erythematosus, Systemic (Phase 4)
Macular Degeneration (Phase 3)
Medication Adherence (Phase 4)
Medicine, Chinese Traditional (Phase 4)
Melanoma (Phase 2)
Mental Health (Phase 2/Phase 3)
Metabolic Syndrome (Phase 4)
Metabolism (Phase 4)
MINOCA (Phase 4)
Mood Disorders (Phase 4)
Mucocutaneous Lymph Node Syndrome (Phase 4)
Multiple Myeloma (Phase 3)
Multiple Pulmonary Nodules (Phase 2)
Multiple Sclerosis (Phase 3)
Multiple Sclerosis, Relapsing-Remitting (Phase 4)
Muscle Spasticity (Phase 4)
Musculoskeletal Diseases (Phase 4)
Mutation (Phase 2)
Myeloproliferative Disorders (Phase 3)
Myocardial Infarction (Phase 4)
Myocardial Ischemia (Phase 4)
Myocardial Reperfusion Injury (Phase 4)
Myocardial Stunning (Phase 4)
Myocardium (Phase 4)
Nasopharyngeal Carcinoma (Phase 2)
Neoplasm Metastasis (Phase 4)
Neoplasms (Phase 4)
Neoplastic Cells, Circulating (Phase 2)
Nerve Block (Phase 4)
Neuralgia, Postherpetic (Phase 1)
Neurofibromatosis 2 (Phase 2)
Neuroma, Acoustic (Phase 2)
Non-alcoholic Fatty Liver Disease (Phase 1/Phase 2)
Non-ST Elevated Myocardial Infarction (Phase 4)
Obesity (Phase 4)
Optic Neuropathy, Ischemic (Phase 2)
Osteoarthritis (Phase 3)
Osteonecrosis (Phase 3)
Osteosarcoma (Phase 4)
Ovarian Hyperstimulation Syndrome (Phase 4)
Ovarian Neoplasms (Phase 4)
Pain ()
Pelvic Pain (Phase 4)
Peptic Ulcer (Phase 4)
Percutaneous Coronary Intervention (Phase 4)
Pericarditis (Phase 4)
Perinatal Death (Phase 3)
Periodontal Diseases (Phase 2)
Periodontitis (Phase 4)
Peripheral Arterial Disease (Phase 4)
Peripheral Vascular Diseases (Phase 4)
Pharmacokinetics (Phase 4)
Pharmacology (Phase 4)
Pharmacology, Clinical (Phase 1)
Pharyngitis (Phase 4)
Pigmentation (Phase 4)
Placenta Diseases (Phase 4)
Placental Insufficiency (Phase 4)
Platelet Aggregation (Phase 4)
Platelet Aggregation Inhibitors (Phase 4)
Platelet Function Tests (Phase 3)
Pneumonia (Phase 2/Phase 3)
Pneumonia, Viral (Phase 2)
Polycythemia Vera (Phase 3)
Polyps (Phase 2/Phase 3)
Postoperative Complications (Phase 2)
Postpartum Period (Early Phase 1)
Precancerous Conditions (Phase 3)
Pre-Eclampsia (Phase 4)
Pregnancy (Phase 4)
Pregnancy Complications (Phase 4)
Pregnancy, High-Risk (Phase 2)
Pregnancy, Twin (Phase 4)
Premature Birth (Phase 4)
Primary Myelofibrosis (Phase 2)
Primary Prevention (Early Phase 1)
Prostatic Neoplasms (Phase 4)
Prostheses and Implants (Phase 4)
Psychotic Disorders (Phase 3)
Pulmonary Disease, Chronic Obstructive (Phase 2)
Pulmonary Embolism (Phase 4)
Purpura, Thrombocytopenic (Phase 2)
Receptors, Purinergic P2Y12 (Phase 4)
Rectal Neoplasms (Phase 2)
Recurrence (Phase 3)
Renal Insufficiency (Phase 3)
Renal Insufficiency, Chronic (Phase 4)
Respiratory Distress Syndrome (Phase 2)
Respiratory Insufficiency (Phase 2)
Respiratory Tract Infections (Phase 4)
Retinal Artery Occlusion (Phase 3)
Retinal Vein Occlusion (Phase 3)
Rheumatic Heart Disease (Phase 3)
Risk Factors (Phase 3)
Sarcoma (Phase 4)
Schizophrenia (Phase 3)
Scleroderma, Systemic (Phase 4)
Secondary Prevention (Phase 3)
Sepsis (Phase 2)
Signs and Symptoms (Phase 1)
Skeleton (Phase 2)
Sleep (Early Phase 1)
Sleep Disorders, Intrinsic (Early Phase 1)
Sleep Initiation and Maintenance Disorders (Early Phase 1)
Smoking (Early Phase 1)
Smoking Cessation (Phase 2)
Splenectomy (Phase 4)
ST Elevation Myocardial Infarction (Phase 4)
Stents (Phase 4)
Stomach Neoplasms (Phase 4)
Stomach Ulcer (Phase 3)
Stress, Psychological (Phase 1/Phase 2)
Stroke ()
Survival (Phase 3)
Tachycardia, Ventricular (Phase 4)
Tension-Type Headache (Phase 4)
Therapeutic Equivalency (Phase 1)
Therapeutics (Phase 2/Phase 3)
Thrombocythemia, Essential (Phase 3)
Thrombocytopenia (Phase 3)
Thromboembolism (Phase 4)
Thrombophilia (Phase 3)
Thrombosis (Phase 4)
Thyroiditis, Autoimmune (Phase 2)
Ticagrelor (Phase 4)
Tobacco (Phase 2)
Tobacco Use Disorder (Phase 2)
Tonsillitis (Phase 4)
Tooth Abnormalities (Early Phase 1)
Transcatheter Aortic Valve Replacement (Phase 4)
Tuberculosis (Phase 2)
Tuberculosis, Meningeal (Phase 3)
Tuberculosis, Multidrug-Resistant (Phase 2)
Tuberculosis, Pulmonary (Phase 2)
Tuberous Sclerosis (Phase 2)
Typhoid Fever (Early Phase 1)
Ulcer (Phase 1)
Upper Extremity Deep Vein Thrombosis (Phase 4)
Urinary Bladder Neoplasms (Phase 4)
Urological Manifestations (Phase 3)
Uterine Cervical Neoplasms (Phase 2)
Uterine Diseases (Phase 2)
Uterine Neoplasms (Phase 2)
Vaccines (Early Phase 1)
Vascular Diseases (Phase 4)
Vascular Endothelial Growth Factor A (Phase 4)
Vascular Grafting (Phase 4)
Venous Thromboembolism (Phase 4)
Venous Thrombosis (Phase 4)
Ventricular Outflow Obstruction (Phase 3)
Ventricular Premature Complexes (Phase 4)
Vertebral Artery Dissection (Phase 3)
Visual Acuity (Phase 3)
Vitamin D Deficiency (Phase 2)
Wounds and Injuries (Phase 4)
| Trial | Phase | Start Date | Organizations | Indications |
|---|
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