setmelanotide Report issue

Biologics Peptide Orphan Drug FDA Approved FDA Breakthrough Therapy FDA Priority Review FDA
AACT ChEMBL DrugBank MeSH PubChem

Active Ingredient History

NOW
  • Now
Setmelanotide, sold under the brand name Imcivree, is a medication used for the treatment of genetic obesity caused by a rare single-gene mutation.   Wikipedia

Chemistry

  • SMILES: C[C@H]1NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](Cc4ccccc4)NC(=O)[C@H](Cc5c[nH]cn5)NC1=O)C(=O)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)C
  • InChIKey: HDHDTKMUACZDAA-PHNIDTBTSA-N
  • Mol. Mass: 1117.33
  • ALogP: Missing data
  • ChEMBL Molecule:
    setmelanotide  
More Chemistry

Pharmacology

  • Mechanisms of Action:
  • Multi-specific: No
  • Black Box: No
  • Availability: Missing data
  • Delivery Methods: Missing data
  • Pro Drug: No

Alternative names

bim-22493 | rm-493 | setmelanotide

Organizations (3)

Research & Development (3)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Marketing (1)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Indications (11)

Approved Indications (0)

Experimental Indications - Clinical Trial Phases 1-4 (11)


 

Alstrom Syndrome (Phase 3)

Bardet-Biedl Syndrome (Phase 3)

Healthy Volunteers (Phase 4)

Melanocortins (Phase 2)

Mutation (Phase 2)

Obesity (Phase 3)

Obesity, Morbid (Phase 1)

Overweight (Phase 2)

Prader-Willi Syndrome (Phase 2)

Renal Insufficiency (Phase 1)

Smith-Magenis Syndrome (Phase 2/Phase 3)

Overview

  • Highest Phase: Phase 4
  • # of Trials: 20
  • # of Trial Organizations: 3

Trials by Phase

Trial Phase Start Date Organizations Indications

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