Active Ingredient History
Reslizumab is a humanized monoclonal antibody against human interleukin-5 (IL-5). Reslizumab binds specifically to IL-5, a key cytokine responsible for the differentiation, maturation, recruitment and activation of human eosinophils. By binding to human IL-5, it blocks its biological function; consequently survival and activity of eosinophils are reduced. The benefits with reslizumab are its ability to reduce the exacerbation rate and improve lung function and asthma-related quality of life in patients with severe eosinophilic asthma and with at least one previous asthma exacerbation in the preceding year. The most common side effects are increased blood creatine phosphokinase, myalgia and anaphylactic reactions. Wikipedia
Drug Pricing (per unit)
Note: This drug pricing data is preliminary, incomplete, and may contain errors.
| Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
|---|
| Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
|---|
Asthma ()
Bronchitis (Phase 2/Phase 3)
Cyclosteroids (Phase 3)
Eosinophilic Esophagitis (Phase 3)
Eosinophils (Phase 3)
Healthy Volunteers (Phase 1)
Hypereosinophilic Syndrome (Phase 2)
Loiasis (Phase 2)
Pharmacokinetics (Phase 1)
Pharmacology (Phase 1)
Sinusitis (Phase 3)
| Trial | Phase | Start Date | Organizations | Indications |
|---|
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