Active Ingredient History

  • Now
Rostafuroxin is a digitoxigenin analog that has been shown to lower blood pressure in an animal model of hypertension. It modulates the effects of the enzyme Na+/K+-ATPase, which maintains sodium and potassium ion gradients across plasma membranes. Rostafuroxin is being studied in clinical trials for the treatment of essential hypertension.   Wikipedia

  • SMILES: C[C@]12CC[C@H](O)C[C@H]1CC[C@@H]3[C@@H]2CC[C@@]4(C)[C@]3(O)CC[C@]4(O)c5cocc5
  • Mol. Mass: 374.52
  • ALogP: 3.99
  • ChEMBL Molecules:
More Chemistry
17-(3-furyl)-5beta-androstane-3,14,17-triol | pst 2238 | pst-2238 | rostafuroxin


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