Active Ingredient History

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Rocuronium (brand names Zemuron, Esmeron) is an aminosteroid non-depolarizing neuromuscular blocker or muscle relaxant used in modern anesthesia to facilitate endotracheal intubation by providing skeletal muscle relaxation, most commonly required for surgery or mechanical ventilation. Rocuronium bromide is a nondepolarizing neuromuscular blocking agent with a rapid to intermediate onset depending on dose and intermediate duration. It acts by competing for cholinergic receptors at the motor end-plate. This action is antagonized by acetylcholinesterase inhibitors, such as neostigmine and edrophonium. Most common adverse reactions are transient hypotension and hypertension.   NCATS

  • SMILES: CC(=O)O[C@H]1[C@H](C[C@H]2[C@@H]3CC[C@H]4C[C@H](O)[C@H](C[C@]4(C)[C@H]3CC[C@]12C)N5CCOCC5)[N+]6(CC=C)CCCC6
  • Mol. Mass: 529.79
  • ALogP: 4.41
  • ChEMBL Molecules:
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Drug Pricing (per unit)

United States

$2.5950 - $6.5360
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Note: This drug pricing data is preliminary, incomplete, and may contain errors.

1-(17-(acetoyl)-3-hydroxy-2-(4-morpholinyl)androstan-16-yl)-1-(2-propenyl)pyrrolidinium | (17 beta)-2-methoxyestra-1,3,5(10)-triene-3,17-diol | 2-hydroxyestradiol 2-methyl ether | 2-hydroxyestradol 2-methyl ether | 2me2 | 2-meoe2 | 2-methoxy-17beta-estradiol | 2-methoxyestra-1(10),2,4-triene-3,17-diol | 2-methoxyestradiol | 2-methoxyestradiol, (17alpha)-isomer | 2-methoxyestradiol-17beta | 2-methoxyestradiol-17 beta | 2-methoxyoestradiol | 2-(methyl-11c)methoxyestradiol | esm | esmeron | esmerone | org 9426 | org-9426 | panzem | pyrrolidinium, 1-((2beta,3alpha,5alpha,16beta,17beta)-17-(acetyloxy)-3-hydroxy-2-(4-morpholinyl)androstan-16-yl)-1-(2-propenyl)-, bromide | rocuronbromid | rocuronium | rocuronium bromide | zemuron


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