Active Ingredient History

  • Now
Bitopertin is a glycine reuptake inhibitor which was under development by Roche as an adjunct to antipsychotics for the treatment of persistent negative symptoms or suboptimally controlled positive symptoms associated with schizophrenia. Research into this indication has been largely halted as a result of disappointing trial results.   Wikipedia

  • SMILES: C[C@H](Oc1ccc(cc1C(=O)N2CCN(CC2)c3ncc(cc3F)C(F)(F)F)S(=O)(=O)C)C(F)(F)F
  • Mol. Mass: 543.46
  • ALogP: 3.94
  • ChEMBL Molecules:
More Chemistry
(4-(3-fluoro-5-trifluoromethylpyridin-2-yl)piperazin-1-yl)(5-methanesulfonyl-2-(2,2,2-trifluoro-1-methylethoxy)phenyl)methanone | bitopertin | rg1678 | rg 1678 | rg-1678 | ro4917838 | ro-4917838


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