Active Ingredient History

NOW
  • Now
Esmethadone, also known as dextromethadone, is the (S)-enantiomer of methadone. It acts as an N-methyl-D-aspartate receptor (NMDAR) antagonist, among other actions. Unlike levomethadone, it has low affinity for opioid receptors and lacks significant respiratory depressant action and abuse liability. Esmethadone is under development for the treatment of major depressive disorder. As of August 2022, it is in phase 3 clinical trials for this indication.   Wikipedia

  • SMILES: CCC(=O)C(C[C@H](C)N(C)C)(C1=CC=CC=C1)C2=CC=CC=C2
  • InChIKey: USSIQXCVUWKGNF-KRWDZBQOSA-N
  • Mol. Mass: 309.4452
  • ALogP: Missing data
  • ChEMBL Molecules: Missing data
More Chemistry
dextromethadone

Feedback

Data collection and curation is an ongoing process for CDEK - if you notice any information here to be missing or incorrect, please let us know! When possible, please include a source URL (we verify all data prior to inclusion).

Report issue