Active Ingredient History

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Drotrecogin alfa (activated) is a recombinant form of human activated protein C that has anti-thrombotic, anti-inflammatory, and profibrinolytic properties. Drotrecogin alpha (activated) belongs to the class of serine proteases. Drotrecogin alfa has not been found to improve outcomes in people with severe sepsis. The manufacturer's aggressive strategies in marketing its use in severe sepsis have been criticized. On October 25, 2011, Eli Lilly & Co. withdrew Xigris from the market after a major study showed no efficacy for the treatment of sepsis.   Wikipedia

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activated protein c | blood coagulation factor xiv (human) | drotrecogin alfa | drotrecogin-alfa | drotrecogin alfa activated | drotrecogin alfa (activated) | drotrecogin alfa, activated | drotrecogin alfa (activated), lyophilized | drotrecognin alpha | recombinant human activated protein c (rh-apc) | rhapc | xigris


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