methylene blue (proveblue) Report issue

Small molecule Orphan Drug FDA Approved FDA Accelerated Approval FDA

Active Ingredient History

  • Now
Methylene blue, also known as methylthioninium chloride, is a medication from WHO's list of essential medicines. Upon administration, methylene blue is converted to leukomethylene blue by erythrocyte methemoblobin reductase in the presence of NADPH. Leukomethylene blue than reduces methemoglobin to oxyhemoglobin, thus restoring oxygen carrying capacity of the blood. Methylene blue is also used as a dye for various diagnostic procedures, for treatment of ifosfamide toxicity and for in vitro staining. Historically, it was used as a photosensitizer for photodynamic therapy for topical treatment of dermatologic or mucocutaneous infections, as an antidote for cyanide poisoning, but these applications are no longer approved. Methylene blue is investigated in clinical trials for treatment of septic shock and Alzheimer's disease.   NCATS

More Chemistry
  • Mechanisms of Action: Missing data
  • Multi-specific: Missing data
  • Black Box: No
  • Availability: Prescription Only
  • Delivery Methods: Parenteral
  • Pro Drug: No

Drug Pricing (per unit)

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Note: This drug pricing data is preliminary, incomplete, and may contain errors.

aizen methylene blue | basic blue 9 | c.i. basic blue 9 | dndi1417128 | lowacryl blue 9 | methylene blue | methylene blue anhydrous | methylene blue cation | methylene blue chloride hydrate | methylenium ceruleum | methylenum coeruleum | methylthionine chloride | methylthionine hcl | methylthioninium | methylthioninium benzalkonium chloride hydrate | methylthioninium chloratum | methylthioninium chloride | methylthioninium chloride hydrate | proveblue | urolene blue


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