Active Ingredient History
Ropivacaine is a member of the amino amide class of local anesthetics and is supplied as the pure S-(-)-enantiomer. It produces effects similar to other local anesthetics via reversible inhibition of sodium ion influx in nerve fibers. Ropivacaine is less lipophilic than bupivacaine and is less likely to penetrate large myelinated motor fibers, resulting in a relatively reduced motor blockade. Thus, ropivacaine has a greater degree of motor-sensory differentiation, which could be useful when the motor blockade is undesirable. The reduced lipophilicity is also associated with decreased potential for central nervous system toxicity and cardiotoxicity. Ropivacaine is indicated for the production of local or regional anesthesia for surgery and for acute pain management. NCATS
Drug Pricing (per unit)
Note: This drug pricing data is preliminary, incomplete, and may contain errors.
| Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
|---|
| Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
|---|
Pain (approved 1996)
Abdominal Pain (Phase 4)
Abdominoplasty (Phase 4)
Acetabularia (Phase 4)
Acute Coronary Syndrome (Phase 4)
Acute Pain (Phase 4)
Administration, Topical (Phase 1)
Amputation (Phase 3)
Analgesia (Phase 4)
Analgesics, Opioid (Phase 4)
Anesthesia (Phase 4)
Anesthesia and Analgesia (Phase 4)
Anesthesia, Conduction (Phase 4)
Anesthesia, Epidural (Phase 4)
Anesthesia, General (Phase 4)
Anesthesia, Local (Phase 4)
Anesthesia, Obstetrical (Phase 3)
Anesthesia Recovery Period (Phase 4)
Anesthesia, Spinal (Phase 3)
Anesthetics (Phase 1)
Anesthetics, Local (Phase 4)
Ankle Fractures (Phase 4)
Anterior Cruciate Ligament Injuries (Phase 4)
Anterior Temporal Lobectomy (Phase 4)
Anxiety (Phase 4)
Aortic Aneurysm, Abdominal (Phase 4)
Appendicitis (Phase 4)
Arm Injuries (Phase 4)
Arrhythmias, Cardiac (Phase 4)
Arterial Occlusive Diseases (Phase 3)
Arthralgia (Phase 3)
Arthritis (Phase 4)
Arthropathy, Neurogenic (Phase 4)
Arthroplasty (Phase 4)
Arthroplasty, Replacement, Hip (Phase 4)
Arthroplasty, Replacement, Knee (Phase 4)
Arthroscopy (Phase 4)
Atrial Fibrillation (Phase 4)
Bariatric Surgery (Phase 4)
Botulinum Toxins, Type A (Phase 1)
Brachial Plexus Block (Phase 3)
Brachial Plexus Neuropathies (Phase 4)
Brain Neoplasms (Phase 4)
Breakthrough Pain (Phase 3)
Breast Diseases (Phase 3)
Breast Neoplasms (Phase 4)
Bronchitis, Chronic (Phase 2)
Bursitis (Phase 4)
Carcinoma, Intraductal, Noninfiltrating (Phase 4)
Carpal Tunnel Syndrome (Phase 4)
Cerebral Palsy (Phase 4)
Cesarean Section (Phase 4)
Chest Pain (Phase 4)
Child (Phase 4)
Cholecystectomy (Phase 4)
Cholecystectomy, Laparoscopic (Phase 4)
Chronic Pain (Phase 4)
Cleft Palate (Early Phase 1)
Colic (Phase 2)
Colonic Neoplasms (Phase 4)
Colorectal Neoplasms (Phase 3)
Colorectal Surgery (Phase 4)
Congenital Abnormalities (Phase 4)
Coronary Artery Bypass (Phase 4)
Coronary Artery Disease (Phase 4)
Delirium (Phase 4)
Dentofacial Deformities (Phase 2)
Dexamethasone (Phase 4)
Dexmedetomidine (Phase 4)
Diabetes Mellitus, Type 2 (Phase 4)
Drug Evaluation (Phase 4)
Drugs, Investigational (Phase 4)
Emergence Delirium (Phase 4)
Episiotomy (Phase 3)
Esophageal Neoplasms (Phase 2)
Fasciitis, Plantar (Phase 1)
Feeding and Eating Disorders (Phase 2)
Femoracetabular Impingement (Phase 4)
Femoral Fractures (Phase 2)
Femoral Neck Fractures (Phase 4)
Fetal Growth Retardation (Phase 3)
Filtration (Phase 4)
Fissure in Ano (Phase 4)
Forearm Injuries (Phase 4)
Fractures, Bone (Phase 4)
Fractures, Closed (Phase 4)
Funnel Chest (Phase 4)
Gender Dysphoria (Phase 4)
General Surgery (Phase 4)
Geriatrics (Phase 2)
Goiter (Phase 3)
Gynecologic Surgical Procedures (Phase 4)
Hallux Valgus (Phase 4)
Hand Injuries (Phase 4)
Headache (Phase 4)
Head and Neck Neoplasms (Phase 2)
Healthy Volunteers (Phase 4)
Heart Diseases (Phase 4)
Heart Valve Diseases (Phase 4)
Hemodynamics (Phase 4)
Hemorrhoids (Phase 4)
Hepatectomy (Phase 3)
Hepatitis C (Phase 1)
Hernia, Inguinal (Phase 4)
Herniorrhaphy (Phase 2)
Hip Dislocation (Phase 4)
Hip Fractures (Phase 4)
Humeral Fractures (Phase 4)
Hyperalgesia (Phase 3)
Hypospadias (Phase 4)
Hypotension (Phase 3)
Hysterectomy (Phase 4)
Intensive Care Units (Phase 3)
Intervertebral Disc Degeneration (Phase 3)
Intestinal Diseases (Phase 4)
Kidney Calculi (Phase 4)
Kidney Failure, Chronic (Phase 4)
Kidney Transplantation (Phase 4)
Knee (Phase 2)
Knee Injuries (Phase 4)
Labor, Obstetric (Phase 3)
Labor Pain (Phase 4)
Laparoscopy (Phase 4)
Laparotomy (Phase 2)
Leg Injuries (Phase 4)
Leg Ulcer (Phase 4)
Leiomyoma (Phase 2)
Leukemia, Lymphoid (Phase 4)
Lidocaine (Phase 3)
Liver Diseases (Phase 4)
Liver Neoplasms (Phase 4)
Low Back Pain (Phase 2)
Lumbar Vertebrae (Phase 3)
Lung Diseases (Phase 4)
Lung Neoplasms (Phase 4)
Mastodynia (Phase 4)
Meniscectomy (Phase 3)
Morphine (Phase 3)
Mouth Abnormalities (Early Phase 1)
Musculoskeletal Diseases (Phase 2/Phase 3)
Myocardium (Phase 4)
Myofascial Pain Syndromes (Phase 3)
Narcotics (Phase 4)
Nausea (Phase 2)
Neck Pain (Phase 4)
Neoplasm Metastasis (Phase 3)
Neoplasms (Phase 2)
Nephrectomy (Phase 4)
Nephrolithotomy, Percutaneous (Phase 4)
Nerve Block (Phase 4)
Nerve Fibers (Phase 4)
Nerve Tissue (Phase 2)
Neuralgia (Phase 4)
Neuralgia, Postherpetic (Phase 4)
Neuromuscular Blockade (Phase 4)
Neurosurgery (Phase 4)
Obesity (Phase 4)
Orthopedic Procedures (Phase 4)
Osteoarthritis (Phase 4)
Osteoarthritis, Hip (Phase 4)
Osteoarthritis, Knee (Phase 4)
Osteotomy (Phase 4)
Ovarian Cysts (Phase 3)
Ovarian Neoplasms (Phase 3)
Pain (Phase 4)
Pain Management (Phase 4)
Pain, Postoperative (Phase 4)
Pain, Procedural (Phase 3)
Pancreatic Diseases (Phase 3)
Pancreatic Neoplasms (Phase 4)
Parturition (Phase 4)
Patient Satisfaction (Phase 4)
Pelvic Floor Disorders (Phase 2/Phase 3)
Penile Diseases (Phase 4)
Personal Satisfaction (Phase 4)
Phantom Limb (Phase 4)
Pharmacokinetics (Phase 4)
Pharmacology (Phase 4)
Physical Therapy Modalities (Phase 4)
Postoperative Complications (Phase 4)
Postoperative Nausea and Vomiting (Phase 4)
Postoperative Period (Phase 4)
Pre-Eclampsia (Phase 3)
Pregnancy (Phase 4)
Prostatic Neoplasms (Phase 4)
Prostheses and Implants (Phase 4)
Pulmonary Atelectasis (Phase 4)
Quality of Life (Phase 4)
Radius Fractures (Phase 4)
Rectal Fistula (Phase 4)
Respiratory Insufficiency (Phase 4)
Respiratory Paralysis (Phase 3)
Rib Fractures (Phase 1)
Ropivacaine (Phase 4)
Rotator Cuff Injuries (Phase 4)
Sciatic Neuropathy (Phase 4)
Shoulder (Phase 4)
Shoulder Dislocation (Phase 2)
Shoulder Fractures (Phase 2)
Shoulder Injuries (Phase 4)
Shoulder Pain (Phase 4)
Sleep Deprivation (Phase 4)
Spinal Diseases (Phase 4)
Spinal Injuries (Phase 3)
Spinal Stenosis (Phase 4)
Spondylolisthesis (Phase 3)
ST Elevation Myocardial Infarction (Phase 4)
Sternotomy (Phase 2/Phase 3)
Stomach Neoplasms (Phase 4)
Stress Disorders, Post-Traumatic (Early Phase 1)
Surgical Procedures, Operative (Phase 4)
Term Birth (Phase 4)
Testicular Diseases (Phase 2)
Therapeutic Uses (Phase 4)
Thoracic Injuries (Phase 4)
Thoracic Surgery (Phase 4)
Thoracotomy (Phase 4)
Thyroid Neoplasms (Phase 3)
Tissues (Phase 2)
Tooth (Phase 4)
Traumatology (Phase 4)
Ulna Fractures (Phase 4)
Upper Extremity (Phase 4)
Urethral Diseases (Phase 4)
Urinary Bladder Neoplasms (Phase 3)
Uterine Prolapse (Phase 4)
Wounds and Injuries (Phase 4)
Wrist Injuries (Phase 4)
| Trial | Phase | Start Date | Organizations | Indications |
|---|
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