Active Ingredient History

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Ropivacaine is a member of the amino amide class of local anesthetics and is supplied as the pure S-(-)-enantiomer. It produces effects similar to other local anesthetics via reversible inhibition of sodium ion influx in nerve fibers. Ropivacaine is less lipophilic than bupivacaine and is less likely to penetrate large myelinated motor fibers, resulting in a relatively reduced motor blockade. Thus, ropivacaine has a greater degree of motor-sensory differentiation, which could be useful when the motor blockade is undesirable. The reduced lipophilicity is also associated with decreased potential for central nervous system toxicity and cardiotoxicity. Ropivacaine is indicated for the production of local or regional anesthesia for surgery and for acute pain management.   NCATS

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Drug Pricing (per unit)

United States

$0.1831 - $120.9792
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Note: This drug pricing data is preliminary, incomplete, and may contain errors.

1-propyl-2',6'-pipecoloxylidide | al 381 | al-381 | anapeine | lea 103 | lea-103 | l-n-n-propylpipecolic acid-2,6-xylidide | narapin | naropeine | naropin | naropine | prf-108 | prf-110 | ropivacaina | ropivacaine | (-)-ropivacaine | ropivacaine hcl | ropivacaine hydrochloride | ropivacaine hydrochloride monohydrate | ropivacaine monohydrochloride | ropivacaine monohydrochloride, (s)-isomer | ropivacainum | ropivicaine | (s)-(−)-1-propyl-2',6'-pipecoloxylidide | (s)-ropivacaine | s-ropivacaine


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