API | formoterol

formoterol (foradil) Report issue

Small molecule Approved ^FDA

AACT ChEMBL DrugBank Drug Central Drugs@FDA KEGG MeSH PubChem repoDB

Active Ingredient History

NOW

Formoterol, also known as eformoterol, is a long-acting β2 agonist (LABA) used as a bronchodilator in the management of asthma and chronic obstructive pulmonary disease (COPD). Formoterol has an extended duration of action compared to short-acting β2 agonists such as salbutamol (albuterol), which are effective for 4 h to 6 h. Formoterol has a relatively rapid onset of action compared to other LABAs, and is effective within 2-3 minutes. The 2022 Global Initiative for Asthma report recommends a combination formoterol/inhaled corticosteroid inhaler as both a preventer and reliever treatment for asthma in adults. In children, a short-actingβ2 agonist is still recommended. ^Wikipedia

Chemistry

SMILES: O.O.COc1ccc(CC(C)NCC(O)c2ccc(O)c(NC=O)c2)cc1.COc3ccc(CC(C)NCC(O)c4ccc(O)c(NC=O)c4)cc3.OC(=O)\C=C\C(=O)O
InChIKey: RATSWNOMCHFQGJ-XODSYJLDSA-N
Mol. Mass: 840.92
ALogP: 2.22 Partition coefficient
ChEMBL Molecules:

formoterol fumarate

formoterol

formoterol fumarate hydrate

None

More Chemistry

Pharmacology

Mechanism of Action:
- Beta-2 adrenergic receptor (Homo sapiens) ^UniProt
Multi-specific: Missing data
Black Box: Yes
Availability: Prescription Only
Delivery Methods: Topical
Pro Drug: No

Drug Pricing (per unit)

United States

$4.4975 - $17.8138

More Pricing Detail

Note: This drug pricing data is preliminary, incomplete, and may contain errors.

Combination drugs

bevespi aerosphere ( glycopyrronium (robinul), formoterol (foradil) )

breztri aerosphere ( glycopyrronium (robinul), formoterol (foradil), budesonide (rhinocort) )

duaklir pressair ( aclidinium (tudorza pressair), formoterol (foradil) )

dulera ( mometasone (elocon), formoterol (foradil) )

symbicort ( formoterol (foradil), budesonide (rhinocort) )

2'-hydroxy-5'-(1-hydroxy-2-((p-methoxy-alpha-methylphenethyl)amino)ethyl)formanilide | 2'-hydroxy-5'-{1-hydroxy-2-[(p-methoxy-alpha-methylphenethyl)amino]ethyl}formanilide | aclidinium bromide / formoterol fumarate dihydrate | aclidinium / formoterol fumarate dihydrate | atimos modulite | bd-40a | beclometasone dipropionate anhydrous / formoterol fumarate dihydrate / glycopyrronium | beclometasone dipropionate / formoterol fumarate dihydrate / glycopyrronium bromide | budesonide / formoterol | budesonide / formoterol fumarate dihydrate | budesonide-formoterol mixt | cgp-25827a | eformoterol | foradil | foradil certihaler | formeterol | formoterol | (+)-formoterol | formoterol fumarate | formoterol fumarate dihydrate | formoterol fumarate hydrate | formoterolum | laba | n-[2-hydroxy-5-(1-hydroxy-2-{[2-(4-methoxyphenyl)-1-methylethyl]amino}ethyl)phenyl]formamide | norflouran | oxis 12 | oxis 6 | performist | perforomist | pt005 | ym-08316

Organizations (209)

Research & Development (206)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Marketing (8)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Indications (37)

Approved Indications (4)

Asthma

Bronchitis, Chronic

Emphysema

Pulmonary Disease, Chronic Obstructive

Experimental Indications - Clinical Trial Phases 1-4 (37)

Airway Management (Phase 4)

Airway Obstruction (Phase 2)

Alzheimer Disease (Phase 2)

Asthma ()

Asthma-Chronic Obstructive Pulmonary Disease Overlap Syndrome (Phase 4)

Asthma, Exercise-Induced (Phase 4)

Bronchiectasis (Phase 4)

Bronchiolitis Obliterans (Phase 2)

Bronchitis (Phase 3)

Bronchitis, Chronic (Phase 4)

Cachexia (Phase 2)

Cognitive Dysfunction (Phase 2)

COVID-19 (Phase 3)

Emphysema ()

Eosinophils (Phase 2/Phase 3)

Exercise (Phase 4)

Healthy Volunteers (Phase 1)

Heart Septal Defects, Ventricular (Phase 4)

Hematopoietic Stem Cell Transplantation (Phase 2)

Hypersensitivity (Phase 2/Phase 3)

Hypoxia (Phase 3)

Idiopathic Pulmonary Fibrosis (Phase 2)

Inflammation (Phase 4)

Lung Diseases (Phase 4)

Lung Diseases, Obstructive (Phase 2/Phase 3)

Lung Neoplasms (Phase 1)

Medication Adherence (Phase 4)

Pharmacological and Toxicological Phenomena (Phase 4)

Pneumonia (Phase 3)

Precancerous Conditions (Phase 1)

Pulmonary Disease, Chronic Obstructive ()

Pulmonary Emphysema (Phase 4)

Quality of Life (Phase 4)

Respiratory Distress Syndrome (Phase 2)

Sleep Disorders, Intrinsic (Phase 3)

Smoking (Phase 3)

Status Asthmaticus (Phase 4)

Overview

Highest Phase: Phase 4
# of Trials: 398
# of Trial Organizations: 206

Trials by Phase

Trial	Phase	Start Date	Organizations	Indications

Feedback

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