Active Ingredient History

  • Now
Atosiban, sold under the brand name Tractocile among others, is an inhibitor of the hormones oxytocin and vasopressin. It is used as an intravenous medication as a labour repressant (tocolytic) to halt premature labor. It was developed by Ferring Pharmaceuticals in Sweden and first reported in the literature in 1985. Originally marketed by Ferring Pharmaceuticals, it is licensed in proprietary and generic forms for the delay of imminent preterm birth in pregnant adult women.   Wikipedia

  • SMILES: CCOc1ccc(C[C@H]2NC(=O)CCSSC[C@H](NC(=O)[C@H](CC(=O)N)NC(=O)[C@@H](NC(=O)[C@@H](NC2=O)[C@@H](C)CC)[C@@H](C)O)C(=O)N3CCC[C@H]3C(=O)N[C@@H](CCCN)C(=O)NCC(=O)N)cc1
  • Mol. Mass: 994.21
  • ALogP: -3.04
  • ChEMBL Molecule:
More Chemistry
  • Mechanism of Action:
  • Multi-specific: Missing data
  • Black Box: No
  • Availability: Missing data
  • Delivery Methods: Missing data
  • Pro Drug: No
1-deamino-2-tyr(oet)-4-thr-8-orn-oxytocin | antocin | antocin ii | atosiban | atosiban acetate | (mpa(1)-d-tyr(et)(2)-thr(4)-orn(8))-oxytocin | (mpa(1),d-tyr(et)2,thr(4),orn(8))oxytocin | orf 22164 | orf-22164 | oxytocin, 1-deamino-o-ethyltyrosyl(2)-threonyl(4)-ornithine(8)- | oxytocin, 1-deamino-(o-et-tyr)(2)-thr(4)-orn(8)- | rwj 22164 | rwj-22164 | tractocil | tractocile


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