Active Ingredient History
Stanol esters is a heterogeneous group of chemical compounds known to reduce the level of low-density lipoprotein (LDL) cholesterol in blood when ingested, though to a much lesser degree than prescription drugs such as statins. The starting material is phytosterols from plants. These are first hydrogenated to give a plant stanol which is then esterified with a mixture of fatty acids also derived from plants. Plant stanol esters are found naturally occurring in small quantities in fruits, vegetables, nuts, seeds, cereals, legumes, and vegetable oils. Wikipedia
| Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
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| Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
|---|
Cardiovascular Diseases (Phase 3)
Coronary Artery Disease (Phase 2/Phase 3)
Dietary Supplements (Phase 4)
Dyslipidemias (Phase 4)
Heart Disease Risk Factors (Phase 4)
Hypercholesterolemia (Phase 4)
Hyperlipidemias (Phase 4)
Metabolic Syndrome (Phase 3)
Osteoporosis (Phase 1)
Postmenopause (Phase 1)
| Trial | Phase | Start Date | Organizations | Indications |
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