Active Ingredient History
Alfuzosin is a quinazoline-derivative alpha-adrenergic blocking agent used to treat hypertension and benign prostatic hyperplasia. Alfuzosin is marketed in the United States by Sanofi Aventis under the brand name Uroxatral. UROXATRAL (alfuzosin HCl extended-release tablets) is indicated for the treatment of the signs and symptoms of benign prostatic hyperplasia. UROXATRAL is not indicated for the treatment of hypertension. Alfuzosin is a non-subtype specific alpha(1)-adrenergic blocking agent that exhibits selectivity for alpha(1)-adrenergic receptors in the lower urinary tract. Inhibition of these adrenoreceptors leads to the relaxation of smooth muscle in the bladder neck and prostate, resulting in the improvement in urine flow and a reduction in symptoms in benign prostate hyperplasia. Alfuzosin also inhibits the vasoconstrictor effect of circulating and locally released catecholamines (epinephrine and norepinephrine), resulting in peripheral vasodilation. NCATS
Drug Pricing (per unit)
Note: This drug pricing data is preliminary, incomplete, and may contain errors.
Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
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Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
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Choroid Diseases (Phase 4)
Constipation (Phase 2)
Erectile Dysfunction (Phase 3)
Healthy Volunteers (Phase 1)
Hydronephrosis (Phase 3)
Kidney Calculi (Phase 3)
Lower Urinary Tract Symptoms (Phase 4)
Multiple Sclerosis (Phase 2/Phase 3)
Nephrolithiasis (Phase 2)
Prostatic Diseases (Phase 4)
Prostatic Neoplasms (Phase 3)
Prostatitis (Phase 3)
Pupil Disorders (Phase 4)
Renal Colic (Phase 4)
Ureteral Diseases (Phase 4)
Ureterolithiasis (Phase 2)
Urinary Bladder Diseases (Phase 3)
Urinary Bladder, Neurogenic (Phase 3)
Urinary Calculi (Phase 3)
Urinary Retention (Phase 3)
Urination Disorders (Phase 3)
Urolithiasis (Phase 2)
Trial | Phase | Start Date | Organizations | Indications |
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