octenidine Report issue

Small molecule Experimental
AACT ChEMBL DrugBank Drug Central KEGG MeSH PubChem

Active Ingredient History

NOW
  • Now
Octenidine dihydrochloride is a cationic surfactant, with a gemini-surfactant structure, derived from pyridine. It is active against Gram-positive and Gram-negative bacteria. Since 1987, it has been used primarily in Europe as an antiseptic prior to medical procedures, including on neonates.   Wikipedia

Chemistry

  • SMILES: CCCCCCCCN=C1C=CN(CCCCCCCCCCN2C=CC(=NCCCCCCCC)C=C2)C=C1
  • InChIKey: ZVXNYZWXUADSRV-UHFFFAOYSA-N
  • Mol. Mass: 550.92
  • ALogP: 9.63
  • ChEMBL Molecules:
    octenidine  
    None  
    octenidine  
More Chemistry

Pharmacology

  • Mechanism of Action:
  • Multi-specific: Missing data
  • Black Box: No
  • Availability: Missing data
  • Delivery Methods: Missing data
  • Pro Drug: No

Alternative names

las189962 | n,n'-(1,10-decanediyldi-1-(4h)-pyridinyl-4-ylidene)bis-(1-octamine) dihydrochloride | n,n'-(1,10-decanediyldi-1(4h)-pyridinyl-4-ylidene)-bis-(1-octanamine) dihydrochloride | octeniderm | octenidine | octenidine chloride | octenidine dihydrochloride | octenidine hcl | octenidine hydrochloride | octenisept | win 41464-2 | win-414642

Organizations (17)

Research & Development (17)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Marketing (0)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Indications (16)

Approved Indications (1)


 

Antisepsis

Experimental Indications - Clinical Trial Phases 1-4 (15)


 

Bacteremia (Phase 4)

Bacterial Infections (Phase 4)

Burns (Phase 3)

Candidiasis (Phase 2)

Catheterization, Central Venous (Phase 4)

Catheter-Related Infections (Phase 4)

Dry Socket (Phase 2)

Eczema (Phase 2)

General Surgery (Phase 2)

Gingivitis (Phase 3)

Leg Ulcer (Phase 4)

Pressure Ulcer (Phase 3)

Tinea Pedis (Phase 2)

Urinary Bladder, Neurogenic (Phase 2/Phase 3)

Wounds and Injuries (Phase 3)

Overview

  • Highest Phase: Phase 4
  • # of Trials: 15
  • # of Trial Organizations: 17

Trials by Phase

Trial Phase Start Date Organizations Indications

Feedback

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