API | nimesulide

nimesulide Report issue

Small molecule Experimental

AACT ChEMBL DrugBank Drug Central KEGG MeSH PubChem

Active Ingredient History

NOW

Nimesulide is a nonsteroidal anti-inflammatory drug (NSAID) with pain medication and fever reducing properties. Its approved indications are the treatment of acute pain, the symptomatic treatment of osteoarthritis, and primary dysmenorrhoea in adolescents and adults above 12 years old. ^Wikipedia

Chemistry

SMILES: CS(=O)(=O)Nc1ccc(cc1Oc2ccccc2)[N+](=O)[O-]
InChIKey: HYWYRSMBCFDLJT-UHFFFAOYSA-N
Mol. Mass: 308.31
ALogP: 2.76 Partition coefficient
ChEMBL Molecules:

aluminum chlorohydrate

nimesulide

More Chemistry

Pharmacology

Mechanism of Action:
- Prostaglandin G/H synthase 2 (Homo sapiens) ^UniProt
Multi-specific: Missing data
Black Box: No
Availability: Missing data
Delivery Methods: Missing data
Pro Drug: No

Organizations (12)

Research & Development (12)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Marketing (0)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Indications (12)

Approved Indications (1)

Analgesia

Experimental Indications - Clinical Trial Phases 1-4 (11)

Breast Neoplasms (Phase 2)

Colorectal Neoplasms (Phase 1)

Dyspepsia (Phase 3)

Inflammation (Phase 3)

Neoplasms (Phase 1)

Osteoarthritis, Knee (Phase 4)

Pain (Phase 2)

Pharyngitis (Phase 4)

Respiratory Tract Infections (Phase 4)

Temporomandibular Joint Disorders (Phase 2)

Temporomandibular Joint Dysfunction Syndrome (Phase 2)

Overview

Highest Phase: Phase 4
# of Trials: 10
# of Trial Organizations: 12

Trials by Phase

Trial	Phase	Start Date	Organizations	Indications

Feedback

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