Active Ingredient History

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Verucerfont (GSK-561,679) is a drug developed by GlaxoSmithKline which acts as a CRF-1 antagonist. Corticotropin releasing factor (CRF), also known as Corticotropin releasing hormone, is an endogenous peptide hormone which is released in response to various triggers such as chronic stress, and activates the two corticotropin-releasing hormone receptors CRH-1 and CRH-2. This then triggers the release of corticotropin (ACTH), another hormone which is involved in the physiological response to stress.   Wikipedia

  • SMILES: CC[C@H](Nc1cc(C)nc2c(c(C)nn12)c3ccc(OC)cc3C)c4onc(C)n4
  • Mol. Mass: 406.49
  • ALogP: 4.58
  • ChEMBL Molecule:
More Chemistry
gsk561679 | gsk 561679 | gsk-561679 | gsk561679a | nbi77860 | nbi 77860 | nbi-77860 | verucerfont


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