Active Ingredient History

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Mexiletine is a non-selective voltage-gated sodium channel blocker which belongs to the Class IB anti-arrhythmic group of medicines. It is used to treat heart arrhythmias. Mexiletine is also used to treat refractory pain and muscle stiffness resulting in myotonic dystrophy or myotonia congenita. Mexiletine was approved for commercial use in 1985 under the brand name Mexitil, but most marketing efforts have since been discontinued. There has been a continued effort to identify other therapeutic use cases and a number of clinical trials have been conducted including ALS and chronic pain from amputation.   NCATS

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Drug Pricing (per unit)

United States

$0.7429 - $1.6479
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Note: This drug pricing data is preliminary, incomplete, and may contain errors.

1-(2',6'-dimethylphenoxy)-2-aminopropane | 1-(2,6-dimethylphenoxy)-2-propanamine | (+-)-1-(2,6-dimethylphenoxy)propan-2-amine | 1-methyl-2-(2,6-xylyloxy)ethanamine | (2rs)-1-(2,6-dimethylphenoxy)-2-aminopropane | dl-mexiletine | ko-1173 cl | ko-1173-cl | mexetil | mexiletina | mexiletine | (+/-)-mexiletine | mexilétine | mexiletine hcl | mexiletine hydrochloride | mexiletin hcl | mexiletin hydrochloride | mexiletinum | mexitil | mexitil p.l. | (rs)-mexiletine


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