Active Ingredient History

  • Now
Mericitabine (RG-7128) is an antiviral drug, a deoxycytidine analog. It was developed as a treatment for hepatitis C, acting as a NS5B RNA polymerase inhibitor, but while it showed a good safety profile in clinical trials, it was not sufficiently effective to be used as a stand-alone agent. However mericitabine has been shown to boost the efficacy of other antiviral drugs when used alongside them, and as most modern treatment regimens for hepatitis C use a combination therapy of several antiviral drugs, clinical trials have continued to see if it can form a part of a clinically useful drug treatment program.   Wikipedia

  • SMILES: CC(C)C(=O)OC[C@H]1O[C@@H](N2C=CC(=NC2=O)N)[C@](C)(F)[C@@H]1OC(=O)C(C)C
  • Mol. Mass: 399.42
  • ALogP: 1.22
  • ChEMBL Molecule:
More Chemistry
2'-fluoro-2'-methyl-3',5'-diisobutyryldeoxycytidine | mericitabine | r7128 | rg7128 | rg 7128 | rg-7128


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