Active Ingredient History

  • Now
Tradipitant is an experimental drug that is a neurokinin 1 antagonist. It works by blocking substance P, a small signaling molecule. Originally, this compound was owned by Eli Lilly and named LY686017. VLY-686 was purchased by Vanda Pharmaceuticals from Eli Lilly and Company in 2012. Vanda Pharmaceuticals is a U.S. pharmaceutical company that as of November 2015 only has three drugs in their product pipeline: tasimelteon, VLY-686, and iloperidone.   Wikipedia

  • SMILES: FC(F)(F)c1cc(Cn2nnc(c3ncccc3C(=O)c4ccccc4Cl)c2c5ccncc5)cc(c1)C(F)(F)F
  • Mol. Mass: 587.91
  • ALogP: 7.37
  • ChEMBL Molecule:
More Chemistry
ly686017 | ly-686017 | tradipitant | vly-686


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