Active Ingredient History

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Lestaurtinib is a tyrosine kinase inhibitor structurally related to staurosporine. This semisynthetic derivative of the indolocarbazole K252a was investigated by Cephalon as a treatment for various types of cancer. It is an inhibitor of the kinases fms-like tyrosine kinase 3 (FLT3), Janus kinase 2 (JAK2), tropomyosin receptor kinase (trk) A (TrkA), TrkB and TrkC.   Wikipedia

  • SMILES: C[C@]12O[C@H](C[C@]1(O)CO)n3c4ccccc4c5c6C(=O)NCc6c7c8ccccc8n2c7c35
  • Mol. Mass: 439.47
  • ALogP: 3.47
  • ChEMBL Molecule:
More Chemistry
a-154475 | a-1544750 | cep701 | cep 701 | cep-701 | kt-555 | kt5555 | kt-5555 | lestaurtinib | sp924 | sp-924 | spm-924


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