lamivudine (epivir) Report issue

Small molecule Approved FDA Accelerated Approval FDA Priority Review FDA

Active Ingredient History

  • Now
Lamivudine is a nucleoside reverse transcriptase inhibitor (NRTI) with activity against Human Immunodeficiency Virus Type 1 (HIV-1) and hepatitis B (HBV). Intracellularly, lamivudine is phosphorylated to its active 5′-triphosphate metabolite, lamivudine triphosphate (3TC-TP). The principal mode of action of 3TC-TP is inhibition of HIV-1 reverse transcriptase (RT) via DNA chain termination after incorporation of the nucleotide analogue. The most common reported adverse reactions in adults are headache, nausea, malaise and fatigue. No data are available regarding interactions with other drugs that have renal clearance mechanisms similar to that of lamivudine.   NCATS

  • SMILES: NC1=NC(=O)N(C=C1)[C@@H]2CS[C@H](CO)O2
  • Mol. Mass: 229.256
  • ALogP: -0.59
  • ChEMBL Molecule:
More Chemistry

Drug Pricing (per unit)

United States

$0.2807 - $51.9767


$0.8465 - $43.4013
More Pricing Detail

Note: This drug pricing data is preliminary, incomplete, and may contain errors.

Combination drugs

( doravirine (pifeltro), tenofovir (viread), lamivudine (epivir) - other name: doravirine/lamivudine/tenofovir disoproxil fumarate 100 mg-300 mg-300 mg oral tablet [delstrigo] )
( dolutegravir (tivicay), lamivudine (epivir) - other names: dolutegravir 50 mg / lamivudine 300 mg oral tablet [dovato], dolutegravir/lamivudine, dolutegravir/lamivudine 50 mg-300 mg oral tablet [dovato], dolutegravir/lamivudine as a single pill, dolutegravir / lamivudine oral tablet, dolutegravir plus lamivudine in a fdc )
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( tenofovir (viread), lamivudine (epivir) - other names: cimduo, temixys )
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( lamivudine (epivir), nevirapine (viramune), zidovudine (retrovir) - other names: lamivudine/nevirapine/zidovudine tablets, lamivudine/zidovudine 150 mg/300 mg tablets co-packaged with nevirapine 200 mg tablets, lamivudine, zidovudine tabs 150mg/300mg co-packaged with nevirapine tabs 200mg )
( efavirenz (sustiva), tenofovir (viread), lamivudine (epivir) - other names: efavirenz, lamivudine,and tenofovir disoproxil fumarate, symfi )
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( abacavir (ziagen), lamivudine (epivir), zidovudine (retrovir) - other name: abacavir sulfate; lamivudine; zidovudine )
(-)-1-((2r,5s)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)cytosine | 2',3'-dideoxy-3'-thiacytidine | (-)-2'-deoxy-3'-thiacytidine | 3tc | 3'-thia-2',3'-dideoxycytidine | abacavir (as sulfate) / lamivudine / zidovudine | abacavir / lamivudine | abacavir sulfate / dolutegravir sodium / lamivudine | beta-l-2',3'-dideoxy-3'-thiacytidine | beta-l-3'-thia-2',3'-dideoxycytidine | combivir | epivir | epivir-hbv | gr-109714x | lamiduvine | lamivudin | lamivudina | lamivudine | lamivudine / raltegravir potassium | lamivudine / zidovudine | lamivudine / zidovudine / abacavir sulfate | lamivudinum | triomune | virolam | zeffix


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