Active Ingredient History
Amoxicillin is one of the widely prescribed antibacterial agents, which was discovered by scientists at Beecham Research Laboratories in 1972. In the US GlaxoSmithKline markets it under the original brand name Amoxil. It is the first line treatment for middle ear infections. It is also used for strep throat, pneumonia, skin infections, and urinary tract infections it is taken by mouth. Amoxicillin inhibits the third and final stage of bacterial cell wall synthesis by preferentially binding to specific penicillin-binding proteins (PBPs) that are located inside the bacterial cell wall. This results in a formation of defective cell wall and a cell death. Common side effects include nausea and rash. It may also increase the risk of yeast infections and, when used in combination with clavulanic acid, diarrhea. It should not be used in those who are allergic to penicillin. NCATS
Drug Pricing (per unit)
Note: This drug pricing data is preliminary, incomplete, and may contain errors.
Combination drugs
| Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
|---|
| Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
|---|
Staphylococcal Skin Infections (approved 1980)
Abscess (Phase 3)
Acute Coronary Syndrome (Phase 4)
Aggressive Periodontitis (Phase 1/Phase 2)
Allergy and Immunology (Phase 4)
Alveolar Bone Loss (Phase 4)
Amoxicillin (Phase 4)
Anti-Bacterial Agents (Phase 4)
Antibiotic Prophylaxis (Phase 4)
Appendicitis (Phase 2)
Arthritis, Infectious (Phase 4)
Bacteremia (Phase 2)
Bacterial Infections (Phase 4)
Bismuth (Phase 4)
Bone Diseases, Infectious (Phase 4)
Child Development (Phase 4)
Chronic Periodontitis (Phase 4)
Colitis, Ulcerative (Phase 2)
Communicable Diseases (Phase 4)
Community-Acquired Infections (Phase 4)
COVID-19 (Phase 3)
Cytochrome P-450 CYP2C19 (Phase 4)
Delivery, Obstetric (Phase 4)
Dental Pulp (Phase 4)
Diabetes Mellitus (Phase 3)
Diarrhea (Phase 4)
Drug Resistance, Bacterial (Phase 4)
Dry Socket (Phase 2)
Dyspepsia (Phase 4)
Endocarditis (Phase 4)
Febrile Neutropenia (Phase 3)
Fetal Membranes, Premature Rupture (Phase 4)
Fever (Phase 4)
Focal Infection, Dental (Phase 4)
Gastritis (Phase 4)
Gastrointestinal Microbiome (Phase 4)
General Surgery (Phase 4)
Graft Survival (Phase 4)
Healthy Volunteers (Phase 1)
Helicobacter Infections (Phase 4)
Helicobacter pylori (Phase 4)
Infant, Premature (Phase 4)
Infection Control (Phase 4)
Infections ()
Inflammation (Phase 4)
Influenza, Human (Phase 1)
Intestinal Neoplasms (Phase 4)
Intraabdominal Infections (Phase 3)
Jaw Fractures (Phase 1)
Lung Diseases (Phase 4)
Malnutrition (Phase 4)
Mandibular Diseases (Phase 4)
Metronidazole (Phase 4)
Mobility Limitation (Early Phase 1)
Myringoplasty (Phase 4)
Neonatal Sepsis (Phase 4)
Obstetric Labor, Premature (Phase 4)
Ofloxacin (Phase 4)
Osteomyelitis (Phase 4)
Otitis Media ()
Pediatric Emergency Medicine (Phase 4)
Penicillins (Phase 4)
Peptic Ulcer (Phase 4)
Peptic Ulcer Hemorrhage (Phase 3)
Peri-Implantitis (Phase 4)
Periodontal Diseases (Phase 4)
Periodontal Pocket (Phase 3)
Periodontitis (Phase 4)
Pharmacokinetics (Phase 4)
Pneumonia ()
Pneumonia, Aspiration (Phase 4)
Postoperative Complications (Phase 4)
Postpartum Period (Phase 4)
Premature Birth (Phase 4)
Primary Prevention (Phase 4)
Prostatic Neoplasms (Phase 4)
Prostheses and Implants (Phase 4)
Puerperal Infection (Phase 4)
Rectal Fistula (Phase 3)
Respiratory Aspiration (Phase 4)
Respiratory Tract Infections (Phase 4)
Root Planing (Phase 4)
Salivary Ducts (Phase 4)
Sinusitis ()
Smoking (Phase 3)
Sprains and Strains (Phase 3)
Stomach Neoplasms (Phase 4)
Stomach Ulcer (Phase 4)
Streptococcus pyogenes (Phase 4)
Surgical Wound Infection (Phase 4)
Temporomandibular Joint Disorders (Phase 4)
Therapeutic Equivalency (Phase 1)
Therapeutics (Phase 4)
Tonsillectomy (Phase 1/Phase 2)
Tonsillitis ()
Tooth Extraction (Phase 4)
Tuberculosis (Phase 3)
Urinary Bladder, Overactive (Phase 4)
Vaginitis (Phase 2)
Wound Infection (Phase 4)
| Trial | Phase | Start Date | Organizations | Indications |
|---|
Feedback
Data collection and curation is an ongoing process for CDEK - if you notice any information here to be missing or incorrect, please let us know! When possible, please include a source URL (we verify all data prior to inclusion).
Report issue
