Active Ingredient History

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Ipatasertib (RG7440) is an experimental cancer drug in development by Roche. It is a small molecule inhibitor of AKT, which is a key component of the PI3K/AKT pathway. It was discovered by Array Biopharma and is currently in phase II trials for treatment of breast cancer.   Wikipedia

  • SMILES: CC(C)NC[C@@H](C(=O)N1CCN(CC1)c2ncnc3[C@H](O)C[C@@H](C)c23)c4ccc(Cl)cc4
  • Mol. Mass: 458.01
  • ALogP: 3.1
  • ChEMBL Molecule:
More Chemistry
2-(4-chlorophenyl)-1-(4-(7-hydroxy-5-methyl-6,7-dihydro-5h-cyclopenta(d)pyrimidin-4-yl)piperazin-1-yl)-3-(isopropylamino)propan-1-one | gdc-0068 | ipatasertib | rg-7440


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