Active Ingredient History

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Epacadostat is an investigational drug for cancer. Epacadostat is an inhibitor of indoleamine 2,3-dioxygenase-1 (IDO1). Epacadostat inhibits IDO1 by competitively blocking it, without interfering with IDO2 or tryptophan 2,3-dioxygenase (TDO). It has antitumor activity in some models, though is most effective when combined with other immunotherapy agents.   Wikipedia

  • SMILES: NS(=O)(=O)NCCNc1nonc1\C(=N\O)\Nc2ccc(F)c(Br)c2
  • Mol. Mass: 438.24
  • ALogP: 0.42
  • ChEMBL Molecule:
More Chemistry
epacadostat | incb024360 | incb-024360


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