API | cyanocobalamin

cyanocobalamin (berocca) Report issue

Small molecule Approved ^FDA

AACT ChEMBL DrugBank Drug Central Drugs@FDA KEGG PubChem repoDB

Active Ingredient History

NOW

Cyanocobalamin is a form of vitamin B12 used to treat vitamin B12 deficiency except in the presence of cyanide toxicity. The deficiency may occur in pernicious anemia, following surgical removal of the stomach, with fish tapeworm, or due to bowel cancer. It is less preferred than hydroxocobalamin for treating vitamin B12 deficiency. Some study have shown that it has an antihypotensive effect. It is used by mouth, by injection into a muscle, or as a nasal spray. ^Wikipedia

Chemistry

SMILES: [57Co+3].[C-]#N.C[C@H](CNC(=O)CC[C@]1(C)[C@@H](CC(N)=O)C2[N-]C1=C(C)C3=NC(=CC4=NC(=C(C)C5=N[C@]2(C)[C@@](C)(CC(N)=O)[C@@H]5CCC(N)=O)[C@@](C)(CC(N)=O)[C@@H]4CCC(N)=O)C(C)(C)[C@@H]3CCC(N)=O)OP([O-])(=O)O[C@@H]6[C@@H](CO)O[C@@H]([C@@H]6O)N7C=[NH]C8=CC(C)=C(C)C=C78
InChIKey: FDJOLVPMNUYSCM-LFHMENBZSA-L
Mol. Mass: 1354.3762
ALogP: Missing data
ChEMBL Molecules:

cyanocobalamin

vitamin b12

More Chemistry

Pharmacology

Mechanism of Action:
Multi-specific: Missing data
Black Box: No
Availability: Prescription Only
Delivery Methods: Oral, Parenteral, Topical
Pro Drug: No

Drug Pricing (per unit)

United States

$1.3549 - $155.0734

More Pricing Detail

Note: This drug pricing data is preliminary, incomplete, and may contain errors.

Combination drugs

berocca pn ( vitamin e, folic acid, cyanocobalamin (berocca), vitamin c, nicotinamide, thiamine, biotin, panthenol, pyridoxine, riboflavin, vitamin a, ergocalciferol (drisdol) - other names: m.v.c, mvc plus )

depinar ( cyanocobalamin (berocca), tannic acid, zinc dichloride )

dicopac ( cyanocobalamin (berocca), cyanocobalamin co-57 (rubratope-57), cyanocobalamin co-58 )

infuvite ( vitamin d3, vitamin e, folic acid, cyanocobalamin (berocca), vitamin c, nicotinamide, thiamine, vitamin k, biotin, panthenol, pyridoxine, riboflavin, vitamin a - other names: infuvite pediatric, infuvite pediatric (pharmacy bulk package) )

m.v.i. adult (pharmacy bulk package) ( vitamin e, folic acid, cyanocobalamin (berocca), vitamin c, nicotinamide, thiamine, vitamin k, biotin, panthenol, pyridoxine, riboflavin, vitamin a, ergocalciferol (drisdol) )

m.v.i. pediatric ( vitamin e, folic acid, cyanocobalamin (berocca), vitamin c, nicotinamide, thiamine, biotin, panthenol, pyridoxine, riboflavin, vitamin a, phytonadione (konakion), ergocalciferol (drisdol) )

vitape ( vitamin e, folic acid, cyanocobalamin (berocca), vitamin c, nicotinamide, thiamine, pantothenic acid, biotin, pyridoxine, riboflavin, vitamin a, phytonadione (konakion), ergocalciferol (drisdol) )

Organizations (181)

Research & Development (144)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Marketing (38)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Indications (88)

Approved Indications (9)

Anemia

Anemia, Iron-Deficiency

Anemia, Pernicious (approved 1949)

Cestode Infections (approved 1949)

Colorectal Neoplasms (approved 1949)

Diabetes Mellitus, Type 2

Folic Acid Deficiency (approved 1949)

Kidney Failure, Chronic

Osteoporosis

Experimental Indications - Clinical Trial Phases 1-4 (82)

Adiposity (Phase 4)

Alzheimer Disease (Phase 3)

Anemia ()

Asthma (Phase 2)

Atherosclerosis (Phase 2/Phase 3)

Bariatric Surgery (Phase 2/Phase 3)

Brain Edema (Phase 2)

Brain Neoplasms (Phase 2)

BRCA1 Protein (Phase 2)

Breast Neoplasms (Phase 2)

Carcinoma, Non-Small-Cell Lung (Phase 3)

Carcinoma, Transitional Cell (Phase 2)

Cardiovascular Diseases (Phase 4)

Cerebral Infarction (Phase 3)

Cognitive Dysfunction (Phase 1)

Coronary Artery Disease (Phase 3)

Coronary Disease (Phase 2)

Depression (Phase 2/Phase 3)

Depressive Disorder (Phase 2)

Diabetes Mellitus, Type 2 ()

Diabetic Retinopathy (Phase 4)

Diarrhea (Phase 2)

Drug Evaluation (Phase 2)

Dyslipidemias (Phase 4)

Endothelial Cells (Phase 2)

Flaviviridae Infections (Phase 4)

Glucose Intolerance (Phase 4)

Head and Neck Neoplasms (Phase 2)

Heart Diseases (Phase 2)

Heart Rate (Phase 1)

Hepatitis B, Chronic (Phase 4)

Hepatitis C (Phase 4)

Hepatitis C, Chronic (Phase 4)

HIV (Phase 2)

Hodgkin Disease (Phase 1/Phase 2)

Hyperhomocysteinemia (Phase 4)

Hypertension (Early Phase 1)

Inflammation (Phase 1)

Iron Deficiencies (Phase 4)

Low Back Pain (Phase 4)

Lung Neoplasms (Phase 2)

Lymphoma, B-Cell (Phase 2)

Lymphoma, Primary Cutaneous Anaplastic Large Cell (Phase 1)

Lymphoma, T-Cell (Phase 2)

Lymphoma, T-Cell, Cutaneous (Phase 1)

Lymphoma, T-Cell, Peripheral (Phase 1/Phase 2)

Menopause (Phase 4)

Mental Health (Phase 2/Phase 3)

Mesothelioma (Phase 2)

Mesothelioma, Malignant (Phase 2)

Mutation (Phase 2)

Mycobacterium tuberculosis (Phase 3)

Mycosis Fungoides (Phase 1)

Myocardial Infarction (Phase 4)

Myocardial Ischemia (Phase 2)

Myocardial Stunning (Phase 4)

Nasopharyngeal Neoplasms (Phase 2)

Neoplasm Metastasis (Phase 2)

Neoplasms (Phase 4)

Obesity (Phase 4)

Osteoporosis (Phase 1)

Pancreatic Neoplasms (Phase 2)

Parkinson Disease (Phase 2/Phase 3)

Pharmacokinetics (Phase 4)

Pharmacology (Phase 1)

Pleura (Phase 2)

Pneumonia (Phase 2)

Polycystic Ovary Syndrome (Phase 4)

Prehypertension (Phase 2)

Prostatic Neoplasms (Phase 2)

Psoriasis (Phase 3)

RNA Virus Infections (Phase 4)

Schizophrenia (Phase 4)

Sepsis (Phase 3)

Sezary Syndrome (Phase 1)

Shock, Septic (Phase 3)

Steatitis (Phase 4)

Stomatitis (Phase 2)

Stroke (Phase 4)

Urinary Bladder Neoplasms (Phase 2)

Vitamin B 12 Deficiency (Phase 4)

Waldenstrom Macroglobulinemia (Phase 1/Phase 2)

Overview

Highest Phase: Phase 4
# of Trials: 103
# of Trial Organizations: 144

Trials by Phase

Trial	Phase	Start Date	Organizations	Indications

Feedback

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