Active Ingredient History

  • Now
2-(1-Hexyloxyethyl)-2-devinyl pyropheophorbide-a (HPPH), a chlorin-based photosensitize, is used in photodynamic therapy. It has been shown the therapeutic potential of HPPH in phase II clinical trials for the treatment of esophageal cancer. Besides, HPPH participated in clinical trials in treating patients with advanced non-small cell lung cancer that blocks the air passages. However, these studies were terminated.   NCATS

  • SMILES: CCCCCCOC(C)C1=C(C)C2=CC3=NC([C@@H](CCC(O)=O)[C@@H]3C)=C4CC(=O)C5=C4NC(C=C6N=C(C=C1N2)C(C)=C6CC)=C5C
  • Mol. Mass: 636.8228
  • ALogP: Missing data
  • ChEMBL Molecules: Missing data
More Chemistry
2-(1-hexyloxyethyl)-2-devinyl pyropheophorbide-a | hpph | photochlor


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