Active Ingredient History

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Guanfacine (marketed under the brand names Estulic, Tenex and the extended release Intuniv) is a sympatholytic drug, indicated for the management of hypertension. Tenex (guanfacine hydrochloride) is an orally active antihypertensive agent whose principal mechanism of action appears to be stimulation of central α2-adrenergic receptors. By stimulating these receptors, guanfacine reduces sympathetic nerve impulses from the vasomotor center to the heart and blood vessels. This results in a decrease in peripheral vascular resistance and a reduction in heart rate. Guanfacine is also used in the treatment of attention deficit hyperactivity disorder. Intuniv is an extended-release version of guanfacine that is used to treat symptoms of ADHD. It can be used by itself or with stimulant medications also used to treat symptoms of ADHD.   NCATS

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Drug Pricing (per unit)

United States

$0.0966 - $6.9052
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Note: This drug pricing data is preliminary, incomplete, and may contain errors.

akfen | bs-100-141 | estulic | guanfacina | guanfacine | guanfacine hcl | guanfacine hydrochloride | guanfacine monohydrochloride | guanfacinum | intuniv | spd503 | tenex


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