tenofovir (viread) Report issue

Small molecule Approved FDA Fast Track FDA Accelerated Approval FDA Priority Review FDA

Active Ingredient History

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CMX157 is a lipid (1-0-hexadecyloxypropyl) conjugate of the acyclic nucleotide analog tenofovir (TFV) with activity against both wild-type and antiretroviral drug-resistant HIV strains, including multidrug nucleoside/nucleotide analog-resistant viruses. CMX157 was designed to mimic lysophosphatidylcholine to take advantage of natural lipid uptake pathways and to achieve high intracellular concentrations of the active antiviral, with the aim of increasing the effectiveness of TFV against wild-type and mutant HIV. CMX157 demonstrated potential to effectively suppress replication of multiNRTI-resistant (MNR) HIV that cannot be treated with any currently available NRTIs, including TDF. It is in phase II clinical trial for HIV infections in USA and phase Ib portion of the phase I/II trial for Hepatitis B in Thailand (PO).   NCATS

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Drug Pricing (per unit)

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Note: This drug pricing data is preliminary, incomplete, and may contain errors.

Combination drugs

( efavirenz (sustiva), tenofovir (viread), emtricitabine (emtriva) - other name: emtricitabine; tenofovir    disoproxil fumarate; efavirenz )
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( doravirine (pifeltro), tenofovir (viread), lamivudine (epivir) - other name: doravirine/lamivudine/tenofovir disoproxil fumarate 100 mg-300 mg-300 mg oral tablet [delstrigo] )
( tenofovir (viread), lamivudine (epivir) - other names: cimduo, temixys )
( tenofovir (viread), emtricitabine (emtriva), cobicistat (stribild), elvitegravir (vitekta) - other name: cobicistat, elvitegravir, emtricitabine, and tenofovir disoproxil fumarate )
( efavirenz (sustiva), tenofovir (viread), lamivudine (epivir) - other names: efavirenz, lamivudine,and tenofovir disoproxil fumarate, symfi )
( tenofovir (viread), emtricitabine (emtriva) - other names: emtricitabine and tenofovir disoproxil fumarate, emtricitabine/tenofovir disoproxil fumarate 200 mg-245 mg oral tablet [truvada], immediate intervention arm truvada in brazil, tenofovir (300mg)/emtricitabine(200mg) [truvada®], tenofovir disoproxil fumarate; emtricitabine, tenofovir disoproxyl fumarate 300 mg plus emtricitabine 200 mg oral tablet )
atripla | bis-isopropyloxycarbonylmethyl-9-(2-phosphonomethoxy)propyl-adenine | bis(isopropyloxymethylcarbonyl) 9-(2-phosphonomethoxypropyl)adenine | bis-poc-pmpa | bis(poc)pmpa | da-2802 | darunavir / cobicistat / emtricitabine / tenofovir alafenamide | efavirenz / emtricitabine / tenofovir disoproxil fumarate | efavirenz / emtricitabine / tenofovir disoproxil maleate | efavirenz / emtricitabine / tenofovir disoproxil, phosphate | efavirenz / emtricitabine / tenofovir disoproxil succinate | elvitegravir / cobicistat / emtricitabine / tenofovir disoproxil fumarate | emtricitabine / rilpivirine hydrochloride /tenofovir disoproxil fumarate | emtricitabine / tenofovir | emtricitabine / tenofovir disoproxil fumarate | emtricitabine / tenofovir disoproxil maleate | emtricitabine, tenofovir disoproxil phosphate | emtricitabine / tenofovir disoproxil succinate | gs-1278 | gs-4331-05 | gsk548470 | pmpa | pmpa prodrug | pro 2000 | pro 2000/5 | tenefovir | tenfofovir | tenfovir | tenofovir | tenofovir bis(isopropyloxycarbonyloxymethyl) ester | tenofovir disoproxil | tenofovir disoproxil aspartate | tenofovir disoproxil fumarate | tenofovir disoproxil phosphate | tenofovir hydrate | tfv | truvada | viread


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