Active Ingredient History

  • Now
Leuprolide acetate is a synthetic nonapeptide analog of naturally occurring gonadotropin-releasing hormone (GnRH or LH-RH). The analog possesses greater potency than the natural hormone. It acts primarily on the anterior pituitary, inducing a transient early rise in gonadotrophin release. With continued use, leuprorelin causes pituitary desensitisation and/or down-regulation, leading to suppressed circulating levels of gonadotrophins and sex hormones. Leuprolide acetate used to treat a wide range of sex hormone-related disorders including advanced prostatic cancer, uterine leiomyomata (fibroids), endometriosis and precocious puberty.   NCATS

  • SMILES: CCNC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](CC(C)C)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CO)NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc5c[nH]cn5)NC(=O)[C@@H]6CCC(=O)N6
  • Mol. Mass: 1209.42
  • ALogP: Missing data
  • ChEMBL Molecules:
More Chemistry
  • Mechanism of Action:
  • Multi-specific: Missing data
  • Black Box: No
  • Availability: Prescription Only
  • Delivery Methods: Oral, Parenteral
  • Pro Drug: No

Combination drugs

( leuprolide (lupron), norethindrone )
abbott-43818 | carcinil | (d-leu(6),des-gly-nh2(10),pro-ethylamide(9))-gonadotropin-releasing hormone | eligard | leupline | leuporelin | leuprolide | leuprolide acetate | leuprolide mesylate | leuprorelin | leuprorelina | leuprorelin acetate | leuproreline | leuprorelinum | lo2a | l-pyroglutamyl-l-histidyl-l-tryptophyl-l-seryl-l-tyrosyl-d-leucyl-l-leucyl-l-arginyl-l-proline ethylamide | lucrine | luprolide acetate gel depot | lupron | lupron depot | lupron depot ped | lupron depot-ped | pglu-his-trp-ser-tyr-d-leu-leu-arg-pro-nhc2h5 | pglu-his-trp-ser-tyr-d-leu-leu-arg-pro-nhet | tap-144 | viadur


Data collection and curation is an ongoing process for CDEK - if you notice any information here to be missing or incorrect, please let us know! When possible, please include a source URL (we verify all data prior to inclusion).

Report issue