Active Ingredient History

  • Now
Desoximetasone (Topicort®) is a topical anti-inflammatory glucocorticoid indicated for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses and for the treatment of plaque psoriasis in patients 18 years of age or older. The topical corticosteroids constitute a class of primarily synthetic steroids used as anti-inflammatory and antipruritic agents. They play a role in cellular signaling, immune function, inflammation and protein regulation; however, the precise mechanism of action in psoriasis is unknown. The mechanism of anti-inflammatory activity of the topical corticosteroids is also unclear. Various laboratory methods, including vasoconstrictor assays, are used to compare and predict potencies and/or clinical efficacies of the topical corticosteroids. There is some evidence to suggest that a recognizable correlation exists between vasoconstrictor potency and therapeutic efficacy in man.   NCATS

  • SMILES: C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@H]1C(=O)CO
  • Mol. Mass: 376.4617
  • ALogP: 2.78
  • ChEMBL Molecules:
More Chemistry
  • Mechanism of Action:
  • Multi-specific: Missing data
  • Black Box: No
  • Availability: Prescription Only
  • Delivery Methods: Missing data
  • Pro Drug: No

Drug Pricing (per unit)

United States

$0.1795 - $102.1200
More Pricing Detail

Note: This drug pricing data is preliminary, incomplete, and may contain errors.

(11beta,16alpha)-9-fluoro-11,21-dihydroxy-16-methylpregna-1,4-diene-3,20-dione | 9alpha-fluoro-16alpha-methyl-delta(1)-corticosterone | a-41-304 | deoxymethasone | desoximetason | desoximetasona | desoximetasone | désoximétasone | desoximetasonum | desoximethasone | desoxymetasone | desoxymethasone | dsxs | hoe-304 | r-2113 | stiedex | stiedex lp | stiedex lpn | topicort | topicort lp


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