Active Ingredient History

  • Now
Ergonovine (also known as ergometrine) is the active water soluble component of ergot of rye. Ergonovine is being used as a maleate salt to prevent or treate postpartum haemorrhage and postabortion haemorrhage. Ergonovine stimulates alpha-adrenergic and serotonin receptors, thus activating contractions of uterine and vascular smooth muscle. Ergonovine may have depressant effect on CNS system as it binds to dopamine receptors.   NCATS

  • SMILES: C[C@@H](CO)NC(=O)[C@H]1CN(C)[C@@H]2Cc3c[nH]c4cccc(C2=C1)c34
  • Mol. Mass: 325.41
  • ALogP: 1.53
  • ChEMBL Molecules:
More Chemistry
(6ar,9r)-7-methyl-4,6,6a,7,8,9-hexahydro-indolo[4,3-fg]quinoline-9-carboxylic acid ((s)-2-hydroxy-1-methyl-ethyl)-amide | [8β(s)]-9,10-didehydro-n-(2-hydroxy-1-methylethyl)-6-methylergoline-8-carboxamide | 9,10-didehydro-n-(2-hydroxy-1-methylethyl)-6-methylergoline-8β(s)-carboxamide | 9,10-didehydro-n-(α-(hydroxymethyl)ethyl)-6-methylergoline-8-β-carboxamide | d-lysergic acid 1-hydroxymethylethylamide | d-lysergic acid-l-propanolamide | ergobasine | ergometrin | ergometrina | ergometrine | ergométrine | ergometrine maleate | ergometrinum | ergonovine | ergonovine maleate | ergostetrine | ergotocine | ergotrate | ergotrate maleate | margonovine | n-(2-hydroxy-1-methylethyl)-d-(+)-lysergamide | n-(α-(hydroxymethyl)ethyl)-d-lysergamide


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