erdosteine Report issue

Small molecule Experimental
AACT ChEMBL DrugBank Drug Central KEGG MeSH PubChem

Active Ingredient History

NOW
  • Now
Erdosteine is a molecule with mucolytic activity. Structurally it is a thiol derivative characterized by the presence of two thiol groups. These two functional sulfhydryl groups contained in the molecule are released following first-pass metabolism with the conversion of erdosteine into its pharmacologically active metabolite Met-I.   Wikipedia

Chemistry

  • SMILES: OC(=O)CSCC(=O)NC1CCSC1=O
  • InChIKey: QGFORSXNKQLDNO-UHFFFAOYSA-N
  • Mol. Mass: 249.31
  • ALogP: -0.05
  • ChEMBL Molecule:
    erdosteine  
More Chemistry

Pharmacology

  • Mechanism of Action:
  • Multi-specific: Missing data
  • Black Box: No
  • Availability: Missing data
  • Delivery Methods: Missing data
  • Pro Drug: No

Alternative names

dithiosteine | dostein | edirel | erdosteine | esteclin | rv 144 | rv-144 | s-(2-(n-3-(2-oxo-tetrahydrothienyl)acetamido))thioglycolic acid | vectrine

Organizations (5)

Research & Development (5)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Marketing (0)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Indications (3)

Approved Indications (1)


 

Pulmonary Disease, Chronic Obstructive

Experimental Indications - Clinical Trial Phases 1-4 (3)


 

Bronchitis, Chronic (Phase 2)

Healthy Volunteers (Phase 1)

Pulmonary Disease, Chronic Obstructive (Phase 4)

Overview

  • Highest Phase: Phase 4
  • # of Trials: 4
  • # of Trial Organizations: 5

Trials by Phase

Trial Phase Start Date Organizations Indications

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