Active Ingredient History

  • Now
Enalapril (marketed as Vasotec in the US, Enaladex and Renitec in some other countries) is an angiotensin-converting-enzyme (ACE) inhibitor used in the treatment of hypertension, diabetic nephropathy, and some types of chronic heart failure. Enalapril, after hydrolysis to enalaprilat, inhibits angiotensin-converting enzyme (ACE) in human subjects and animals. ACE is a peptidyl dipeptidase that catalyzes the conversion of angiotensin I to the vasoconstrictor substance, angiotensin II. Angiotensin II also stimulates aldosterone secretion by the adrenal cortex. The beneficial effects of enalapril in hypertension and heart failure appear to result primarily from suppression of the renin-angiotensin-aldosterone system. Inhibition of ACE results in decreased plasma angiotensin II, which leads to decreased vasopressor activity and to decrease aldosterone secretion.   NCATS

More Chemistry
  • Mechanism of Action:
  • Multi-specific: Missing data
  • Black Box: Yes
  • Availability: Prescription Only
  • Delivery Methods: Parenteral
  • Pro Drug: No

Drug Pricing (per unit)

United States

$0.0000 - $24.7697


$0.0556 - $0.2667
More Pricing Detail

Note: This drug pricing data is preliminary, incomplete, and may contain errors.

1-(n-((s)-1-carboxy-3-phenylpropyl)-l-alanyl)-l-proline 1'-ethyl ester | analapril | ednyt | enalapril | enalaprila | enalapril acid | enalaprilat | enalaprilat anhydrous | enalaprilat dihydrate | enalaprilate | enalaprilat hydrate | enalaprilic acid | enalapril maleate | enalaprilum | enapren | enarenal | innovace | lexxel | mk-421 | mk-422 | pralenal 10 | pralenal 20 | pralenal 2.5 | pralenal 5 | renitec | (s)-1-(n-(1-(ethoxycarbonyl)-3-phenylpropyl)-l-alanyl)-l-proline | (s)-1-{(s)-2-[1-((s)-ethoxycarbonyl)-3-phenyl-propylamino]-propionyl}-pyrrolidine-2-carboxylic acid | vaseretic | vasotec | xanef


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