Active Ingredient History

  • Now
Emivirine (MKC-442) is a failed experimental agent for the treatment of HIV. It is a non-nucleoside reverse transcriptase inhibitor. While emivirine showed promising antiviral activity in vitro, it failed to show sufficient efficacy in human trials. However it is still notable as an early proof of concept, which led to the discovery of a number of related antiviral drugs.   Wikipedia

  • SMILES: CCOCN1C(=O)NC(=O)C(=C1Cc2ccccc2)C(C)C
  • Mol. Mass: 302.37
  • ALogP: 2.24
  • ChEMBL Molecule:
More Chemistry
1-(ethoxymethyl)-5-(1-methylethyl)-6-(phenylmethyl)pyrimidine-2,4(1h,3h)-dione | 2,4(1h,3h)-pyrimidinedione, 1-(ethoxymethyl)-5-(1-methylethyl)-6-(phenylmethyl)- | 6-benzyl-1-(ethoxymethyl)-5-(1-methylethyl)uracil | 6-benzyl-1-(ethoxymethyl)-5-isopropyluracil | 6-benzyl-1-ethoxymethyl-5-isopropyluracil | coactinon | emivirine | mkc 442 | mkc-442


Data collection and curation is an ongoing process for CDEK - if you notice any information here to be missing or incorrect, please let us know! When possible, please include a source URL (we verify all data prior to inclusion).

Report issue