Active Ingredient History

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Fibroblast growth factor receptor 1 (FGFR1), also known as basic fibroblast growth factor receptor 1, fms-related tyrosine kinase-2 / Pfeiffer syndrome, and CD331, is a receptor tyrosine kinase whose ligands are specific members of the fibroblast growth factor family. FGFR1 has been shown to be associated with Pfeiffer syndrome, and clonal eosinophilias.   Wikipedia

  • SMILES: CN1CCN(CC1)c2ccc3nc([nH]c3c2)C4=C(N)c5c(F)cccc5NC4=O
  • Mol. Mass: 392.44
  • ALogP: 2.54
  • ChEMBL Molecules:
More Chemistry
4-amino-5-fluoro-3-(5-(4-methylpiperazin-1-yl)-1h-benzimidazol-2-yl)quinolin-2(1h)-one | chir258 | chir 258 | chir-258 | dovitinib | dovitinib lactate | gfki-258 | nvp-tki258 | tki258 | tki 258 | tki-258


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