Active Ingredient History

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Docusate, also known as docusate salts or dioctyl sulfosuccinate, prevents/relieves dry hard stool and thus is used to treat constipation. Results usually occurs 1 to 3 days after the first dose. In North America, docusate and a stimulant laxative such as sennosides are commonly used in bowel treatment protocols associated with institutionalized elderly and oncology treatments. A paucity of evidence is available to support the use of the stool softener docusate yet it continues to be prescribed in everyday clinical practice for the aforementioned populations. While the actual cost of docusate is low, additional costs associated with its administration (i.e. nursing time) and its widespread use can be significant. Docusate is absorbed into the bloodstream and excreted via the gallbladder after undergoing extensive metabolism. The effect of docusate may not necessarily be all due to its surfactant properties. Perfusion studies suggest that docusate inhibits fluid absorption or stimulates secretion in the portion of the small intestine known as the jejunum   NCATS

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Drug Pricing (per unit)

United States

$0.0090 - $1.9960


$0.0532 - $5.4271
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Note: This drug pricing data is preliminary, incomplete, and may contain errors.

audinorm | clear ear | colace | correctol stool softener laxative | dialose | dioctyl | dioctyl disodium sulfosuccinate | dioctyl sodium sulfosuccinate | dioctyl sulfosuccinate | dioctyl sulfosuccinic acid | docusate | docusate calcium | docusate salts | docusate sodium | docusol | docusol 100 | doxinate | d-s-s | ducosate sodium | dulcoease | e480 | fletchers' enemette | klyx | modane soft | molcer | molofac | norgalax | sodium dioctyl sulfosuccinate | soliwax | waxsol


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